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Cartilage formation in a hollow fiber bioreactor studied by proton magnetic resonance microscopy

Overview of attention for article published in Matrix Biology, November 1998
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (61st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

patent
1 patent

Citations

dimensions_citation
50 Dimensions

Readers on

mendeley
10 Mendeley
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Title
Cartilage formation in a hollow fiber bioreactor studied by proton magnetic resonance microscopy
Published in
Matrix Biology, November 1998
DOI 10.1016/s0945-053x(98)90099-3
Pubmed ID
Authors

K. Potter, J.J. Butler, C. Adams, K.W. Fishbein, E.W. McFarland, W.E. Horton, R.G.S. Spencer

Abstract

The ideal in vitro system for investigating the regulation of cartilage formation and maintenance would allow for three-dimensional tissue growth, a wide range of biochemical interventions, and non-destructive evaluation. We have developed a hollow fiber bioreactor (HFBR) system which meets these criteria. After injection with embryonic chick sternal chondrocytes, neocartilage is elaborated around the hollow fibers, reaching a thickness of up to a millimeter after four weeks of growth. This process was monitored over time with nuclear magnetic resonance (NMR) microimaging and correlative biochemical and histologic analyses. Tissue volume and cellularity increased greatly during development. This was accompanied by changes in magnetic resonance properties consistent with increased macromolecular content. Further, tissue heterogeneity, observed as regional variations in cell size in histologic sections, was also observed in quantitative NMR images.

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 10%
Unknown 9 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 40%
Unspecified 3 30%
Other 1 10%
Lecturer > Senior Lecturer 1 10%
Researcher 1 10%
Other 0 0%
Readers by discipline Count As %
Engineering 4 40%
Unspecified 3 30%
Medicine and Dentistry 2 20%
Agricultural and Biological Sciences 1 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 December 2008.
All research outputs
#3,524,698
of 12,288,335 outputs
Outputs from Matrix Biology
#161
of 708 outputs
Outputs of similar age
#98,543
of 265,073 outputs
Outputs of similar age from Matrix Biology
#4
of 11 outputs
Altmetric has tracked 12,288,335 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 708 research outputs from this source. They receive a mean Attention Score of 3.2. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 265,073 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.