Title |
Epigenetic modifications of caveolae associated proteins in health and disease
|
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Published in |
BMC Genomic Data, June 2015
|
DOI | 10.1186/s12863-015-0231-y |
Pubmed ID | |
Authors |
Jin-Yih Low, Helen D. Nicholson |
Abstract |
Caveolae are small, "omega-shaped" invaginations at the plasma membrane of the cell which are involved in a variety of processes including cholesterol transport, potocytosis and cell signalling. Within caveolae there are caveolae-associated proteins, and changes in expression of these molecules have been described to play a role in the pathophysiology of various diseases including cancer and cardiovascular disease. Evidence is beginning to accumulate that epigenetic processes may regulate the expression of these caveolae related genes, and hence contribute to disease progression. Here, we summarize the current knowledge of the role of epigenetic modification in regulating the expression of these caveolae related genes and how this relates to changes in cellular physiology and in health and disease. |
X Demographics
Geographical breakdown
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France | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
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Unknown | 29 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 8 | 28% |
Student > Bachelor | 3 | 10% |
Other | 2 | 7% |
Student > Postgraduate | 2 | 7% |
Student > Master | 2 | 7% |
Other | 5 | 17% |
Unknown | 7 | 24% |
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Agricultural and Biological Sciences | 4 | 14% |
Medicine and Dentistry | 2 | 7% |
Unspecified | 1 | 3% |
Arts and Humanities | 1 | 3% |
Other | 2 | 7% |
Unknown | 12 | 41% |