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Healing activity of Casearia sylvestris Sw. in second-degree scald burns in rodents

Overview of attention for article published in BMC Research Notes, June 2015
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  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

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1 X user
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1 patent

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Title
Healing activity of Casearia sylvestris Sw. in second-degree scald burns in rodents
Published in
BMC Research Notes, June 2015
DOI 10.1186/s13104-015-1251-4
Pubmed ID
Authors

Evandro Pedro de Campos, Letícia Nava Trombini, Rafaela Rodrigues, Décio Luis Portella, Adriana Carolina Werner, Miriele Cristina Ferraz, Robson Vicente Machado de Oliveira, José Carlos Cogo, Yoko Oshima-Franco, Norberto Aranha, Marli Gerenutti

Abstract

Every year thousands of people are victims of burns, mainly scald burns. Many of these victims have small size wounds and superficial partial thickness and do not seek specialized medical care. As in Brazil Casearia sylvestris Sw., popularly known as guaçatonga is widely used for its analgesic, antiseptic and anti-inflammatory activities, this study sought to evaluate the effects of its hydroalcoholic extract in healing process of burns injuries. The obtained extract was validated applying a thin layer chromatography and sophisticated validation method using Bothrops jararacussu snake venom that is necrotic and inflammatory, and by which guaçatonga extract was able to neutralize the irreversible neuromuscular blockade induced by the venom. After induction of the scald injury, the animals were treated daily with saline solution spray; spray containing extract; biofilm; or biofilm impregnated with extract. Significant differences were observed between the four groups studied considering: extension of the healing area, neovascularization, fibroblast proliferation, and epithelialization. The anti-inflammatory and bactericidal effects of C. sylvestris Sw. suggests a potential therapeutic benefit in the treatment of inflammatory conditions in second-degree scald burn injuries, as well as, counteracting against the in vitro paralysis induced by B. jararacussu venom.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 64 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 16%
Student > Ph. D. Student 7 11%
Student > Master 7 11%
Student > Doctoral Student 6 9%
Student > Postgraduate 3 5%
Other 8 13%
Unknown 23 36%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 13%
Medicine and Dentistry 7 11%
Biochemistry, Genetics and Molecular Biology 7 11%
Pharmacology, Toxicology and Pharmaceutical Science 5 8%
Nursing and Health Professions 2 3%
Other 10 16%
Unknown 25 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 February 2023.
All research outputs
#7,489,867
of 23,545,680 outputs
Outputs from BMC Research Notes
#1,191
of 4,303 outputs
Outputs of similar age
#86,197
of 264,942 outputs
Outputs of similar age from BMC Research Notes
#17
of 80 outputs
Altmetric has tracked 23,545,680 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 4,303 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,942 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.