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Positive impact of retrograde autologous priming in adult patients undergoing cardiac surgery: a randomized clinical trial

Overview of attention for article published in Journal of Cardiothoracic Surgery, May 2018
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Title
Positive impact of retrograde autologous priming in adult patients undergoing cardiac surgery: a randomized clinical trial
Published in
Journal of Cardiothoracic Surgery, May 2018
DOI 10.1186/s13019-018-0739-0
Pubmed ID
Authors

Britt Hofmann, Claudia Kaufmann, Markus Stiller, Thomas Neitzel, Andreas Wienke, Rolf-Edgar Silber, Hendrik Treede

Abstract

Adult cardiac surgery with extracorporeal circulation is known to be associated with increased risk of blood transfusion leading to adverse outcomes. Procedures like retrograde autologous priming (RAP) may reduce these negative side effects. This randomized prospective study was initiated to assess whether RAP using specifically designed RAP bag (Terumo) has immediate effects on patient outcome. One hundred eighteen adults undergoing elective CABG or elective aortic valve replacement were randomly assigned by a computer program into two groups: the RAP group (n = 54) in which the retrograde autologous priming was applied and the non-RAP (n = 64) group in which the same setting was used without the possibility to save priming volume. Patient demographics, preoperative characteristics and postoperative outcomes were analyzed for both groups. The primary endpoint defined as rate of intraoperative blood transfusion was significantly reduced in the RAP-group (p = 0.04). The absolute risk reduction for RAP managed patients was 13.5 percent points. There were no significant differences in operation time and blood loss. No deaths and no myocardial infarctions were observed. The number of patients needed to treat to prevent at least one red blood cell transfusion was around 8 (NNT = 7.42). Retrograde autologous priming is a safe and less invasive procedure which achieves clear benefits for adult cardiac surgery patients. In the light of increasing red blood cell transfusion risks and costs and the wish of patients to avoid a transfusion implementation of retrograde autologous priming is an interesting option. German Clinical Trials Register ID: DRKS00013512 , registered 04 December 2017.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 73 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 10 14%
Student > Bachelor 8 11%
Student > Doctoral Student 6 8%
Other 6 8%
Student > Master 6 8%
Other 11 15%
Unknown 26 36%
Readers by discipline Count As %
Medicine and Dentistry 34 47%
Nursing and Health Professions 4 5%
Unspecified 2 3%
Biochemistry, Genetics and Molecular Biology 2 3%
Agricultural and Biological Sciences 1 1%
Other 2 3%
Unknown 28 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 October 2018.
All research outputs
#17,961,293
of 23,065,445 outputs
Outputs from Journal of Cardiothoracic Surgery
#546
of 1,250 outputs
Outputs of similar age
#238,806
of 330,191 outputs
Outputs of similar age from Journal of Cardiothoracic Surgery
#16
of 57 outputs
Altmetric has tracked 23,065,445 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,250 research outputs from this source. They receive a mean Attention Score of 2.2. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,191 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.