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Aging-associated increase in indoleamine 2,3-dioxygenase (IDO) activity appears to be unrelated to the transcription of the IDO1 or IDO2 genes in peripheral blood mononuclear cells

Overview of attention for article published in Immunity & Ageing, October 2011
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  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

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1 X user

Citations

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34 Mendeley
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Title
Aging-associated increase in indoleamine 2,3-dioxygenase (IDO) activity appears to be unrelated to the transcription of the IDO1 or IDO2 genes in peripheral blood mononuclear cells
Published in
Immunity & Ageing, October 2011
DOI 10.1186/1742-4933-8-9
Pubmed ID
Authors

Saara Marttila, Juulia Jylhävä, Carita Eklund, Antti Hervonen, Marja Jylhä, Mikko Hurme

Abstract

Old age is associated with increased levels of circulating pro-inflammatory cytokines, a phenomenon termed inflamm-aging. Elevated levels of pro-inflammatory cytokines have been associated with several age-associated diseases and with a shortened lifespan. Indoleamine 2,3-dioxygenase (IDO) has immunomodulatory properties and its activity is elevated in inflammation, autoimmune disorders and malignancies. We have previously shown that IDO activity is increased in nonagenarians compared to young individuals and that high IDO activity is associated with mortality at old age.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Italy 1 3%
Unknown 32 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 29%
Researcher 6 18%
Student > Bachelor 3 9%
Student > Postgraduate 3 9%
Student > Doctoral Student 2 6%
Other 2 6%
Unknown 8 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 24%
Biochemistry, Genetics and Molecular Biology 5 15%
Medicine and Dentistry 5 15%
Immunology and Microbiology 2 6%
Nursing and Health Professions 1 3%
Other 2 6%
Unknown 11 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 October 2011.
All research outputs
#15,237,301
of 22,655,397 outputs
Outputs from Immunity & Ageing
#239
of 366 outputs
Outputs of similar age
#94,232
of 135,959 outputs
Outputs of similar age from Immunity & Ageing
#1
of 5 outputs
Altmetric has tracked 22,655,397 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 366 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.9. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 135,959 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them