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Mendeley readers
Attention Score in Context
| Title |
Glucose deprivation in tuberous sclerosis complex-related tumors
|
|---|---|
| Published in |
Cell & Bioscience, October 2011
|
| DOI | 10.1186/2045-3701-1-34 |
| Pubmed ID | |
| Authors |
Xiuyun Jiang, Heidi L Kenerson, Raymond S Yeung |
| Abstract |
Cancer cells possess unique metabolic phenotypes that are determined by their underlying oncogenic pathways. Activation of the PI3K/Akt/mTOR signaling cascade promotes glycolysis and leads to glucose-dependence in tumors. In particular, cells with constitutive mTORC1 activity secondary to the loss of TSC1/TSC2 function are prone to undergo apoptosis upon glucose withdrawal in vitro, but this concept has not been tested in vivo. This study examines the effects of restricting glucose metabolism by pharmacologic and dietary means in a tuberous sclerosis complex (TSC) tumor xenograft model. |
Mendeley readers
The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| United States | 1 | 2% |
| Unknown | 44 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 22% |
| Student > Ph. D. Student | 8 | 17% |
| Student > Master | 5 | 11% |
| Other | 4 | 9% |
| Student > Bachelor | 3 | 7% |
| Other | 9 | 20% |
| Unknown | 7 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 14 | 30% |
| Medicine and Dentistry | 10 | 22% |
| Biochemistry, Genetics and Molecular Biology | 5 | 11% |
| Neuroscience | 2 | 4% |
| Psychology | 1 | 2% |
| Other | 3 | 7% |
| Unknown | 11 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 October 2011.
All research outputs
#2,667,187
of 22,655,397 outputs
Outputs from Cell & Bioscience
#47
of 913 outputs
Outputs of similar age
#14,731
of 139,967 outputs
Outputs of similar age from Cell & Bioscience
#1
of 5 outputs
Altmetric has tracked 22,655,397 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 913 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 139,967 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them