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Evaluation of cytokines produced by β-hemolytic streptococcus in acute pharyngotonsillitis

Overview of attention for article published in Brazilian Journal of Otorhinolaryngology, July 2015
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Title
Evaluation of cytokines produced by β-hemolytic streptococcus in acute pharyngotonsillitis
Published in
Brazilian Journal of Otorhinolaryngology, July 2015
DOI 10.1016/j.bjorl.2015.05.003
Pubmed ID
Authors

Sydney Correia Leão, Ivanna Oliveira Leal, Hertaline Menezes do Nascimento Rocha, Tania Maria de Andrade Rodrigues

Abstract

The most common pathogen in bacterialpharyngotonsillitis is group A β-hemolytic streptococcus, although groups B, C, F,and G have also been associated with pharyngotonsillitis. To assess the levels of the cytokines TNF-α, IL-6,IL-4, and IL-10 in bacterial pharyngotonsillitis caused by group A and non-A(groups B, C, F and G) β-hemolytic streptococcus. Thestudy was conducted at a pediatric emergency care unit. The sample comprised children(5-9 years old) with acute bacterial pharyngotonsillitis diagnosed between December of 2011and May of 2012. The research involved collection of blood samples from thepatients, enzyme-linked immunosorbent assay detection of TNF-α, IL-6,IL-4, and IL-10, and collection of two oropharyngeal swabs for bacterial isolation. Additionally, themedical history of the study participants was also collected. In the studied group (mean age: 5.93 years), higher pharyngotonsillitis incidencewas observed in the female gender (64.76%). Higher incidence of tonsillar exudateswas observed with groups A and C. No statistically significant differences incytokine levels were observed among groups. However, the group A and the control group showed a differencein the IL-6 level (p=0.0016). The Groups A and C showed higher cytokine levels thanthe Groups B and control, suggesting similar immunological patterns.

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Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 2 12%
Researcher 2 12%
Student > Master 2 12%
Student > Bachelor 2 12%
Librarian 1 6%
Other 2 12%
Unknown 6 35%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 18%
Medicine and Dentistry 3 18%
Chemistry 2 12%
Computer Science 1 6%
Agricultural and Biological Sciences 1 6%
Other 1 6%
Unknown 6 35%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 July 2015.
All research outputs
#19,063,563
of 21,423,731 outputs
Outputs from Brazilian Journal of Otorhinolaryngology
#5
of 8 outputs
Outputs of similar age
#203,384
of 245,602 outputs
Outputs of similar age from Brazilian Journal of Otorhinolaryngology
#1
of 1 outputs
Altmetric has tracked 21,423,731 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8 research outputs from this source. They receive a mean Attention Score of 0.7. This one scored the same or higher as 3 of them.
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