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X Demographics
Mendeley readers
Attention Score in Context
| Title |
An interactive reference framework for modeling a dynamic immune system
|
|---|---|
| Published in |
Science, July 2015
|
| DOI | 10.1126/science.1259425 |
| Pubmed ID | |
| Authors |
Matthew H Spitzer, Pier Federico Gherardini, Gabriela K Fragiadakis, Nupur Bhattacharya, Robert T Yuan, Andrew N Hotson, Rachel Finck, Yaron Carmi, Eli R Zunder, Wendy J Fantl, Sean C Bendall, Edgar G Engleman, Garry P Nolan |
| Abstract |
Immune cells function in an interacting hierarchy that coordinates the activities of various cell types according to genetic and environmental contexts. We developed graphical approaches to construct an extensible immune reference map from mass cytometry data of cells from different organs, incorporating landmark cell populations as flags on the map to compare cells from distinct samples. The maps recapitulated canonical cellular phenotypes and revealed reproducible, tissue-specific deviations. The approach revealed influences of genetic variation and circadian rhythms on immune system structure, enabled direct comparisons of murine and human blood cell phenotypes, and even enabled archival fluorescence-based flow cytometry data to be mapped onto the reference framework. This foundational reference map provides a working definition of systemic immune organization to which new data can be integrated to reveal deviations driven by genetics, environment, or pathology. |
X Demographics
The data shown below were collected from the profiles of 21 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 14% |
| United States | 3 | 14% |
| Japan | 2 | 10% |
| India | 1 | 5% |
| France | 1 | 5% |
| Australia | 1 | 5% |
| Unknown | 10 | 48% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 17 | 81% |
| Science communicators (journalists, bloggers, editors) | 2 | 10% |
| Scientists | 2 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 658 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 10 | 2% |
| United Kingdom | 4 | <1% |
| Switzerland | 3 | <1% |
| Germany | 3 | <1% |
| Japan | 3 | <1% |
| France | 2 | <1% |
| Korea, Republic of | 1 | <1% |
| Sweden | 1 | <1% |
| South Africa | 1 | <1% |
| Other | 6 | <1% |
| Unknown | 624 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 176 | 27% |
| Researcher | 176 | 27% |
| Other | 43 | 7% |
| Student > Master | 39 | 6% |
| Student > Postgraduate | 29 | 4% |
| Other | 110 | 17% |
| Unknown | 85 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 206 | 31% |
| Immunology and Microbiology | 104 | 16% |
| Biochemistry, Genetics and Molecular Biology | 94 | 14% |
| Medicine and Dentistry | 68 | 10% |
| Engineering | 23 | 3% |
| Other | 69 | 10% |
| Unknown | 94 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 28. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 December 2023.
All research outputs
#1,338,092
of 24,981,585 outputs
Outputs from Science
#21,427
of 80,399 outputs
Outputs of similar age
#16,443
of 268,662 outputs
Outputs of similar age from Science
#517
of 1,252 outputs
Altmetric has tracked 24,981,585 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 80,399 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 65.0. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,662 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 1,252 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.