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Cadmium: From Toxicity to Essentiality

Overview of attention for book
Attention for Chapter 4: Determination of Cadmium in Biological Samples
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About this Attention Score

  • Among the highest-scoring outputs from this source (#47 of 134)
  • Above-average Attention Score compared to outputs of the same age (55th percentile)

Mentioned by

wikipedia
3 Wikipedia pages

Citations

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113 Dimensions

Readers on

mendeley
35 Mendeley
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Chapter title
Determination of Cadmium in Biological Samples
Chapter number 4
Book title
Cadmium: From Toxicity to Essentiality
Published in
Metal ions in life sciences, February 2016
DOI 10.1007/978-94-007-5179-8_4
Pubmed ID
Book ISBNs
978-9-40-075178-1, 978-9-40-075179-8
Authors

Katrin Klotz, Wobbeke Weistenhöfer, Hans Drexler, Klotz, Katrin, Weistenhöfer, Wobbeke, Drexler, Hans

Abstract

Analyses of cadmium concentrations in biological material are performed using inductively coupled plasma mass spectrometry (ICP-MS) and atomic absorption spectrometry (AAS), but also electrochemical methods, neutron activation analysis (NAA), and X-ray fluorescence spectrometry (XRF). The predominant sample matrices include blood, plasma, serum, and urine, as well as hair, saliva, and tissue of kidney cortex, lung, and liver. While cadmium in blood reveals rather the recent exposure situation, cadmium in urine reflects the body burden and is an indicator for the cumulative long term exposure.After chronic exposure, cadmium accumulates in the human body and causes kidney diseases, especially lesions of proximal tubular cells. A tubular proteinuria causes an increase in urinary excretion of microproteins. Excretions of retinol binding protein (RBP), β2-microglobulin (β2-M), and α1-microglobulin are validated biomarkers for analyzing cadmium effects. For this purpose, immunological procedures such as ELISA, and radio- and latex-immunoassays are used.However, proteinuria is not specific to cadmium, but can also occur after exposure to other nephrotoxic agents or due to various kidney diseases. In summary, cadmium in urine and blood are the most specific biomarkers of cadmium exposure. A combination of parameters of exposure (cadmium in blood, cadmium in urine) and parameters of effect (e.g., β2-M, RBP) is required to reveal cadmium-induced nephrological effects.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Sri Lanka 1 3%
Unknown 34 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 26%
Student > Master 6 17%
Researcher 5 14%
Other 2 6%
Student > Ph. D. Student 2 6%
Other 4 11%
Unknown 7 20%
Readers by discipline Count As %
Chemistry 8 23%
Medicine and Dentistry 5 14%
Environmental Science 2 6%
Earth and Planetary Sciences 2 6%
Nursing and Health Professions 1 3%
Other 8 23%
Unknown 9 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 April 2020.
All research outputs
#7,451,284
of 22,780,165 outputs
Outputs from Metal ions in life sciences
#47
of 134 outputs
Outputs of similar age
#127,752
of 400,602 outputs
Outputs of similar age from Metal ions in life sciences
#7
of 22 outputs
Altmetric has tracked 22,780,165 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 134 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 400,602 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.