For mitosis aficionados, this may provide some relief. Typically, when DNA comes near the cortex during mitosis, there is a DECREASE in actin level and not an increase, as seen in cleavage stage embryos. This causes blebbing at the poles of mitotic cells.
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Open Access UCL Research: Kinetochore-localized PP1-Sds22 couples chromosome segregation to polar relaxation https://t.co/2ZOIokT72i
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Our Nature paper. Nature. 2015 Aug 27;524(7566):489-92. doi: 10.1038/nature14496. https://t.co/Av3UkWTWWD
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Pubmed: Kinetochore-localized PP1-Sds22 couples chromosome segregation to polar relaxation. http://t.co/pxq1FXs1Oj