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X Demographics
Mendeley readers
| Title |
Anti‐tumor activities and apoptotic mechanism of ribosome‐inactivating proteins
|
|---|---|
| Published in |
Cancer Communications, July 2015
|
| DOI | 10.1186/s40880-015-0030-x |
| Pubmed ID | |
| Authors |
Meiqi Zeng, Manyin Zheng, Desheng Lu, Jun Wang, Wenqi Jiang, Ou Sha |
| Abstract |
Ribosome-inactivating proteins (RIPs) belong to a family of enzymes that attack eukaryotic ribosomes and potently inhibit cellular protein synthesis. RIPs possess several biomedical properties, including anti-viral and anti-tumor activities. Multiple RIPs are known to inhibit tumor cell proliferation through inducing apoptosis in a variety of cancers, such as breast cancer, leukemia/lymphoma, and hepatoma. This review focuses on the anti-tumor activities of RIPs and their apoptotic effects through three closely related pathways: mitochondrial, death receptor, and endoplasmic reticulum pathways. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 56 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 18% |
| Student > Bachelor | 8 | 14% |
| Student > Master | 7 | 13% |
| Researcher | 4 | 7% |
| Student > Doctoral Student | 2 | 4% |
| Other | 6 | 11% |
| Unknown | 19 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 15 | 27% |
| Agricultural and Biological Sciences | 11 | 20% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 11% |
| Medicine and Dentistry | 2 | 4% |
| Engineering | 1 | 2% |
| Other | 0 | 0% |
| Unknown | 21 | 38% |