Too Basic: APP β-CTF's YENTPY Motif Binds Proton Pump, Thwarts Lysosomes
Alzforum,
26 Jul 2023 The rap sheet for β-CTF is growing longer. The C-terminal fragment, produced when β-secretase cleaves APP, binds to—a…
26 Jul 2023 The rap sheet for β-CTF is growing longer. The C-terminal fragment, produced when β-secretase cleaves APP, binds to—a…
A C-terminal fragment of APP recruits the protein APPL1 to endosomes, causing the enlarged, overactive vesicles seen early in…