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Genetic analysis of porcine circovirus type 2 from pigs affected with PMWS in Chile reveals intergenotypic recombination

Overview of attention for article published in Virology Journal, October 2017
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Title
Genetic analysis of porcine circovirus type 2 from pigs affected with PMWS in Chile reveals intergenotypic recombination
Published in
Virology Journal, October 2017
DOI 10.1186/s12985-017-0850-1
Pubmed ID
Authors

Victor Neira, Natalia Ramos, Rodrigo Tapia, Juan Arbiza, Andrónico Neira-Carrillo, Manuel Quezada, Álvaro Ruiz, Sergio A. Bucarey

Abstract

Porcine circovirus type 2 (PCV2) is a very small, non-enveloped and icosahedral virus, with circular single stranded DNA genome. This virus is the most ubiquitous and persistent pathogen currently affecting the swine industry worldwide. PCV2 has been implicated as the major causative agent of postweaning multisystemic wasting syndrome (PMWS), a disease which is characterized by severe immunosuppressive effects in the porcine host. Worldwide PCV2 isolates have been classified into four different genotypes, PCV2a, PCV2b, PCV2c and PCVd. The goal of this work was to conduct the first phylogenetic analysis of PCV2 in Chile. PCV2 partial ORF2 sequences (462 nt) obtained from 29 clinical cases of PMWS in 22 Chilean intensive swine farms, covering over the 90% of the local pork-production, were analyzed. 14% and 52% of sequences belonged to the genotypes PCV2a and PCV2b, respectively. Surprisingly, 34% of sequences were PCV2a/PCV2d recombinant viruses. Our findings suggested that a novel cluster of Chilean sequences emerged resulting from intergenotypic recombination between PCV2a and PCV2d.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 18%
Student > Bachelor 5 15%
Student > Doctoral Student 4 12%
Student > Ph. D. Student 3 9%
Student > Master 2 6%
Other 4 12%
Unknown 10 29%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 12 35%
Biochemistry, Genetics and Molecular Biology 5 15%
Agricultural and Biological Sciences 4 12%
Immunology and Microbiology 1 3%
Medicine and Dentistry 1 3%
Other 0 0%
Unknown 11 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2018.
All research outputs
#20,516,195
of 23,083,773 outputs
Outputs from Virology Journal
#2,903
of 3,068 outputs
Outputs of similar age
#282,024
of 323,260 outputs
Outputs of similar age from Virology Journal
#48
of 53 outputs
Altmetric has tracked 23,083,773 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
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