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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Relationship between circulating VCAM-1, ICAM-1, E-selectin and MMP9 and the extent of coronary lesions
|
|---|---|
| Published in |
Clinics, May 2018
|
| DOI | 10.6061/clinics/2018/e203 |
| Pubmed ID | |
| Authors |
Jéssica Cavalcante dos Santos, Marina Sampaio Cruz, Raul Hernandes Bortolin, Katiene Macêdo de Oliveira, Jéssica Nayara Góes de Araújo, Victor Hugo Rezende Duarte, Ananília Medeiros Gomes da Silva, Isabelle Cristina Clemente dos Santos, Juliana Marinho de Oliveira Dantas, Maria Sanali Moura de Oliveira Paiva, Adriana Augusto Rezende, Mario Hiroyuki Hirata, Rosario Dominguez Crespo Hirata, André Ducati Luchessi, Vivian Nogueira Silbiger |
| Abstract |
Inflammatory molecules play a role in the development of atherosclerosis, which is the primary origin of cardiovascular disorders. However, to the best of our knowledge, no study has attempted to investigate the relationship between these circulating molecules and the prediction of cardiovascular risk. The present study aimed to investigate the relationships of vascular cell adhesion molecule-1, intercellular adhesion molecule-1, E-selectin and matrix metalloproteinase 9 serum concentrations with the extent of coronary lesions. Seventy-four individuals who were undergoing coronary angiography for the first time for diagnostic purposes were enrolled in this study. The extent of the coronary lesion was assessed using the Friesinger Index, and subjects were classified into four groups: no lesions, minor lesions, intermediate lesions and major lesions. Serum biochemical parameters and serum concentrations of vascular cell adhesion molecule-1, intercellular adhesion molecule-1, E-selectin and matrix metalloproteinase 9 were analyzed. The vascular cell adhesion molecule-1 concentration was higher than 876 ng/mL in individuals with intermediate and major lesions (p<0.001 and p=0.020, respectively). Moreover, logistic regression analysis showed that these patients had an increased risk of having an intermediate lesion (p=0.007). Interestingly, all individuals with major lesions had vascular cell adhesion molecule-1 concentrations higher than 876 ng/mL. No association was found between the concentrations of the other proteins and the Friesinger Index. Serum vascular cell adhesion molecule-1 may be associated with the extent of coronary lesions. Moreover, it may represent an alternative to improve the cardiovascular risk classification in patients without acute coronary syndrome. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 53 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 8 | 15% |
| Researcher | 6 | 11% |
| Student > Postgraduate | 5 | 9% |
| Student > Bachelor | 5 | 9% |
| Student > Ph. D. Student | 4 | 8% |
| Other | 7 | 13% |
| Unknown | 18 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 26% |
| Biochemistry, Genetics and Molecular Biology | 5 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 6% |
| Neuroscience | 2 | 4% |
| Agricultural and Biological Sciences | 2 | 4% |
| Other | 7 | 13% |
| Unknown | 20 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2018.
All research outputs
#17,292,294
of 25,382,440 outputs
Outputs from Clinics
#667
of 1,215 outputs
Outputs of similar age
#222,509
of 344,432 outputs
Outputs of similar age from Clinics
#10
of 17 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,215 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,432 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.