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Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway

Overview of attention for article published in Journal of Experimental & Clinical Cancer Research, October 2011
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1 X user
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3 Facebook pages

Citations

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60 Dimensions

Readers on

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27 Mendeley
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Title
Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway
Published in
Journal of Experimental & Clinical Cancer Research, October 2011
DOI 10.1186/1756-9966-30-103
Pubmed ID
Authors

Weiru Xu, Hongsheng Lin, Ying Zhang, Xinyi Chen, Baojin Hua, Wei Hou, Xin Qi, Yingxia Pei, Xiaoyun Zhu, Zhizheng Zhao, Liangliang Yang

Abstract

Cancer stem cells (CSCs) play an important role in cancer initiation, relapse and metastasis. To date, no specific medicine has been found to target CSCs as they are resistant to most conventional therapies and proliferate indefinitely. Compound Kushen Injection (CKI) has been widely used for cancer patients with remarkable therapeutic effects in Chinese clinical settings for many years. This study focused on whether CKI could inhibit MCF-7 SP cells in vitro and in vivo.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 4%
Unknown 26 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 22%
Researcher 5 19%
Student > Postgraduate 3 11%
Student > Ph. D. Student 3 11%
Student > Master 2 7%
Other 2 7%
Unknown 6 22%
Readers by discipline Count As %
Medicine and Dentistry 9 33%
Agricultural and Biological Sciences 5 19%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Psychology 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 2 7%
Unknown 7 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2016.
All research outputs
#15,739,010
of 25,371,288 outputs
Outputs from Journal of Experimental & Clinical Cancer Research
#930
of 2,378 outputs
Outputs of similar age
#99,170
of 152,772 outputs
Outputs of similar age from Journal of Experimental & Clinical Cancer Research
#11
of 16 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,378 research outputs from this source. They receive a mean Attention Score of 4.8. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 152,772 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.