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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Delay in treatment intensification increases the risks of cardiovascular events in patients with type 2 diabetes
|
|---|---|
| Published in |
Cardiovascular Diabetology, August 2015
|
| DOI | 10.1186/s12933-015-0260-x |
| Pubmed ID | |
| Authors |
Sanjoy K Paul, Kerenaftali Klein, Brian L Thorsted, Michael L Wolden, Kamlesh Khunti |
| Abstract |
The aim of the study was to evaluate the effect of delay in treatment intensification (IT; clinical inertia) in conjunction with glycaemic burden on the risk of macrovascular events (CVE) in type 2 diabetes (T2DM) patients. A retrospective cohort study was carried out using United Kingdom Clinical Practice Research Datalink, including T2DM patients diagnosed from 1990 with follow-up data available until 2012. In the cohort of 105,477 patients mean HbA1c was 8.1% (65 mmol/mol) at diagnosis, 11% had a history of cardiovascular disease, and 7.1% experienced at least one CVE during 5.3 years of median follow-up. In patients with HbA1c consistently above 7/7.5% (53/58 mmol/mol, n = 23,101/11,281) during 2 years post diagnosis, 26/22% never received any IT. Compared to patients with HbA1c <7% (<53 mmol/mol), in patients with HbA1c ≥7% (≥53 mmol/mol), a 1 year delay in receiving IT was associated with significantly increased risk of MI, stroke, HF and composite CVE by 67% (HR CI: 1.39, 2.01), 51% (HR CI: 1.25, 1.83), 64% (HR CI: 1.40, 1.91) and 62% (HR CI: 1.46, 1.80) respectively. One year delay in IT in interaction with HbA1c above 7.5% (58 mmol/mol) was also associated with similar increased risk of CVE. Among patients with newly diagnosed T2DM, 22% remained under poor glycaemic control over 2 years, and 26% never received IT. Delay in IT by 1 year in conjunction with poor glycaemic control significantly increased the risk of MI, HF, stroke and composite CVE. |
X Demographics
The data shown below were collected from the profiles of 34 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 11 | 32% |
| United Kingdom | 5 | 15% |
| Mexico | 2 | 6% |
| Argentina | 1 | 3% |
| Venezuela, Bolivarian Republic of | 1 | 3% |
| Colombia | 1 | 3% |
| Saudi Arabia | 1 | 3% |
| Australia | 1 | 3% |
| Unknown | 11 | 32% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 25 | 74% |
| Scientists | 4 | 12% |
| Practitioners (doctors, other healthcare professionals) | 4 | 12% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 264 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 3 | 1% |
| United Kingdom | 1 | <1% |
| Mexico | 1 | <1% |
| Unknown | 259 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 32 | 12% |
| Student > Master | 31 | 12% |
| Student > Ph. D. Student | 23 | 9% |
| Student > Bachelor | 22 | 8% |
| Unspecified | 21 | 8% |
| Other | 75 | 28% |
| Unknown | 60 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 95 | 36% |
| Unspecified | 21 | 8% |
| Nursing and Health Professions | 16 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 14 | 5% |
| Biochemistry, Genetics and Molecular Biology | 8 | 3% |
| Other | 31 | 12% |
| Unknown | 79 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 46. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 October 2021.
All research outputs
#833,962
of 24,080,653 outputs
Outputs from Cardiovascular Diabetology
#34
of 1,489 outputs
Outputs of similar age
#10,805
of 268,187 outputs
Outputs of similar age from Cardiovascular Diabetology
#2
of 25 outputs
Altmetric has tracked 24,080,653 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,489 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,187 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.