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A new intern asked if amp-sulbactam was a good choice for acute cholangitis and I said no. Not only is GNR resistance high in our area, but a new study suggests definitive therapy w/ anaerobic coverage does not improve outcomes absent anaerobic bacteremia.
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Biliary tract infections. If you don't isolate anaerobes then you don't need anaerobic cover. https://t.co/P0XfU07GCB
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Anaerobic coverage as definitive therapy does not affect clinical outcomes in community-onset bact... https://t.co/zufLnZr78A #bmcinfectdis