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Morphometric study of the corpus cavernosum after anabolic androgenic steroid administration in pubertal and adult rats

Overview of attention for article published in Acta Cirurgica Brasileira, July 2015
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1 Google+ user

Citations

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6 Dimensions

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8 Mendeley
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Title
Morphometric study of the corpus cavernosum after anabolic androgenic steroid administration in pubertal and adult rats
Published in
Acta Cirurgica Brasileira, July 2015
DOI 10.1590/s0102-865020150070000005
Pubmed ID
Authors

Alessandro de Sousa Mendes de Sena, Rafael Areas Vargas, Diogo Benchimol De Souza, Waldemar Silva Costa, Francisco José Sampaio

Abstract

To evaluate the penile morphological modifications of pubertal and adult rats chronically treated with supra-physiological doses of anabolic androgenic steroids. Forty-eight male Wistar rats were distributed into four groups: two control groups, 105- and 65-day-old (C105 and C65, respectively) injected with peanut oil (vehicle); and two treated groups, 105- and 65-day-old (T105 and T65, respectively) injected with nandrolone decanoate at a dose of 10 mg Kg-1 of body weight. The rats were injected once a week for eight weeks. The rats were then killed and their penises were processed for histomorphometric analyses. The mean of each parameter was statistically compared. A corpus cavernosum reduction of 12.5% and 10.9% was observed in the T105 and T65 groups, respectively, when compared with their respective control groups. The cavernosum smooth muscle surface density diminished by 5.6% and 12.9% in the T65 and T105 groups, respectively, when compared with their controls. In contrast, the sinusoidal space increased by 17% in the T105 group and decreased by 9.6% in the T65 group. The use of supra-physiological doses of AAS promotes structural changes in the rat penis, by altering the proportions of corpus cavernosum tissues, in both pubertal and adult treated animals.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 25%
Unspecified 1 13%
Student > Doctoral Student 1 13%
Professor > Associate Professor 1 13%
Student > Master 1 13%
Other 0 0%
Unknown 2 25%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 1 13%
Unspecified 1 13%
Nursing and Health Professions 1 13%
Agricultural and Biological Sciences 1 13%
Social Sciences 1 13%
Other 2 25%
Unknown 1 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2015.
All research outputs
#8,095,350
of 13,444,886 outputs
Outputs from Acta Cirurgica Brasileira
#53
of 129 outputs
Outputs of similar age
#115,377
of 236,674 outputs
Outputs of similar age from Acta Cirurgica Brasileira
#1
of 1 outputs
Altmetric has tracked 13,444,886 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 129 research outputs from this source. They receive a mean Attention Score of 1.7. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 236,674 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them