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RNA binding properties of the US11 protein from four primate simplexviruses

Overview of attention for article published in Virology Journal, November 2011
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  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

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Title
RNA binding properties of the US11 protein from four primate simplexviruses
Published in
Virology Journal, November 2011
DOI 10.1186/1743-422x-8-504
Pubmed ID
Authors

Sarah Tohme, Cyprian D Cukier, Alberto Severini

Abstract

The protein encoded by the Us11 gene of herpes simplex viruses is a dsRNA binding protein which inhibits protein kinase R activity, thereby preventing the interferon-induced shut down of protein synthesis following viral infection. Us11 protein is not essential for infectivity in vitro and in mice in herpes simplex virus type 1 (HSV1), however this virus has a second, and apparently more important, inhibitor of PKR activity, the γ134.5 protein. Recently sequenced simian simplexviruses SA8, HVP2 and B virus do not have an ORF corresponding to the γ134.5 protein, yet they have similar, or greater, infectivity as HSV1 and HSV2.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 2 25%
Student > Doctoral Student 2 25%
Researcher 2 25%
Student > Bachelor 1 13%
Unknown 1 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 50%
Biochemistry, Genetics and Molecular Biology 1 13%
Medicine and Dentistry 1 13%
Unknown 2 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 November 2011.
All research outputs
#13,357,126
of 22,656,971 outputs
Outputs from Virology Journal
#1,349
of 3,022 outputs
Outputs of similar age
#86,405
of 141,801 outputs
Outputs of similar age from Virology Journal
#34
of 92 outputs
Altmetric has tracked 22,656,971 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,022 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.5. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 141,801 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 92 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.