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Mendeley readers
| Chapter title |
Deregulation of RNA Metabolism in Microsatellite Expansion Diseases
|
|---|---|
| Chapter number | 8 |
| Book title |
RNA Metabolism in Neurodegenerative Diseases
|
| Published in |
Advances in neurobiology, January 2018
|
| DOI | 10.1007/978-3-319-89689-2_8 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-989688-5, 978-3-31-989689-2
|
| Authors |
Chaitali Misra, Feikai Lin, Auinash Kalsotra, Misra, Chaitali, Lin, Feikai, Kalsotra, Auinash |
| Abstract |
RNA metabolism impacts different steps of mRNA life cycle including splicing, polyadenylation, nucleo-cytoplasmic export, translation, and decay. Growing evidence indicates that defects in any of these steps lead to devastating diseases in humans. This chapter reviews the various RNA metabolic mechanisms that are disrupted in Myotonic Dystrophy-a trinucleotide repeat expansion disease-due to dysregulation of RNA-Binding Proteins. We also compare Myotonic Dystrophy to other microsatellite expansion disorders and describe how some of these mechanisms commonly exert direct versus indirect effects toward disease pathologies. |
Mendeley readers
The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 25 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 28% |
| Researcher | 6 | 24% |
| Student > Master | 3 | 12% |
| Student > Bachelor | 1 | 4% |
| Professor | 1 | 4% |
| Other | 2 | 8% |
| Unknown | 5 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 11 | 44% |
| Agricultural and Biological Sciences | 5 | 20% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
| Medicine and Dentistry | 1 | 4% |
| Neuroscience | 1 | 4% |
| Other | 1 | 4% |
| Unknown | 5 | 20% |