Title |
Optimized Production of Xylitol from Xylose Using a Hyper-Acidophilic Candida tropicalis
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Published in |
Biomolecules, August 2015
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DOI | 10.3390/biom5031979 |
Pubmed ID | |
Authors |
Elena Tamburini, Stefania Costa, Maria Gabriella Marchetti, Paola Pedrini |
Abstract |
The yeast Candida tropicalis DSM 7524 produces xylitol, a natural, low-calorie sweetener, by fermentation of xylose. In order to increase xylitol production rate during the submerged fermentation process, some parameters-substrate (xylose) concentration, pH, aeration rate, temperature and fermentation strategy-have been optimized. The maximum xylitol yield reached at 60-80 g/L initial xylose concentration, pH 5.5 at 37 °C was 83.66% (w/w) on consumed xylose in microaerophilic conditions (kLa = 2·h(-1)). Scaling up on 3 L fermenter, with a fed-batch strategy, the best xylitol yield was 86.84% (w/w), against a 90% of theoretical yield. The hyper-acidophilic behaviour of C. tropicalis makes this strain particularly promising for industrial application, due to the possibility to work in non-sterile conditions. |
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Mendeley readers
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