We haven't measured this directly, but Occam's Razor tells me that the biases we observed must also apply to #CRISPR #Cas9 induced mutations and their repair. It would fit with epigenetic state determining #CRISPR efficiency, e.g., https://t.co/nYmWNMM7bJ
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When you have a nightmare about something, wake up and google it, and find out it's true. https://t.co/OgYn4pGWCF
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A team at Tongji University present DeepCRISPR: a comprehensive computational platform to unify #sgRNA on-target and off-target site prediction into one framework with #deeplearning: https://t.co/vBiXHPbDkd #CRISPR https://t.co/fseMVyru1P
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RT @CRISPR_papers: DeepCRISPR: optimized CRISPR guide RNA design by deep learning. https://t.co/Fi2A5J2VTj