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CXCL16 in Vascular Pathology Research: from Macro Effects to microRNAs

Overview of attention for article published in Journal of atherosclerosis and thrombosis, January 2015
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Mentioned by

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4 tweeters

Citations

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13 Dimensions

Readers on

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14 Mendeley
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Title
CXCL16 in Vascular Pathology Research: from Macro Effects to microRNAs
Published in
Journal of atherosclerosis and thrombosis, January 2015
DOI 10.5551/jat.29942
Pubmed ID
Authors

Ivan Jovanović, Maja Zivković, Tamara Djurić, Milan Popović, Dragan Alavantić, Aleksandra Stanković

Abstract

Chemokines and their receptors have become significant factors in atherosclerosis research. CXCL16 is a multifunctional agent located on a separate locus to all other known chemokines and binds only to its "unique" receptor named CXCR6. As a scavenger receptor, adhesion molecule, and chemokine, it quickly became an interesting target in atherosclerosis research as all its functions have a role in vascular pathology. The investigation of the role of CXCL16 in atherosclerosis, although shown in in vitro studies, animal knockout models, and CXCL16 gene polymorphisms, haplotypes, and circulating levels, still shows puzzling results. Genetic and epigenetic studies have just scratched the surface of research necessary for a better assessment of the significance and perspective of this marker in plaque development and progression. In this review, we will summarize current knowledge about CXCL16 in atherosclerosis. Additionally, we will point out the importance of bioinformatics tools for the detection of potentially new CXCL16 regulatory networks through microRNA activity. This review aims to provide a better understanding of the underlying mechanisms, define more specific biomarkers, and discover new therapeutic targets.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 36%
Student > Ph. D. Student 2 14%
Professor 1 7%
Student > Bachelor 1 7%
Student > Master 1 7%
Other 1 7%
Unknown 3 21%
Readers by discipline Count As %
Medicine and Dentistry 2 14%
Biochemistry, Genetics and Molecular Biology 2 14%
Immunology and Microbiology 2 14%
Agricultural and Biological Sciences 2 14%
Computer Science 1 7%
Other 1 7%
Unknown 4 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2015.
All research outputs
#7,537,322
of 12,499,297 outputs
Outputs from Journal of atherosclerosis and thrombosis
#200
of 405 outputs
Outputs of similar age
#116,073
of 238,353 outputs
Outputs of similar age from Journal of atherosclerosis and thrombosis
#1
of 1 outputs
Altmetric has tracked 12,499,297 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 405 research outputs from this source. They receive a mean Attention Score of 2.5. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 238,353 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them