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Molecular identification of Saint Louis encephalitis virus genotype IV in Colombia

Overview of attention for article published in Memórias do Instituto Oswaldo Cruz, August 2015
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Title
Molecular identification of Saint Louis encephalitis virus genotype IV in Colombia
Published in
Memórias do Instituto Oswaldo Cruz, August 2015
DOI 10.1590/0074-02760280040
Pubmed ID
Authors

Richard Hoyos-López, Sandra Uribe Soto, Guillermo Rúa-Uribe, Juan Carlos Gallego-Gómez

Abstract

Saint Louis encephalitis virus (SLEV) is a member of the Japanese-encephalitis virus serocomplex of the genus Flavivirus. SLEV is broadly distributed in the Americas and the Caribbean Islands, where it is usually transmitted by mosquitoes of the genus Culex and primarily to birds and mammalian-hosts. Humans are occasionally infected by the virus and are dead-end hosts. SLEV causes encephalitis in temperate regions, while in tropical regions of the Americas, several human cases and a wide biological diversity of SLEV-strains have been reported. The phylogenetic analysis of the envelope (E) protein genes indicated eight-genotypes of SLEV with geographic overlap. The present paper describes the genotyping of two SLEV viruses detected in mosquito-pools collected in northern Colombia (department of Cordoba). We used reverse transcription-polymerase chain reaction to amplify a fragment of theE-gene to confirm the virus identity and completeE-gene sequencing for phylogenetic analysis and genotyping of the two-SLEV viruses found circulating in Córdoba. This is the first report of SLEV genotype IV in Colombia (Córdoba) in mosquitoes from a region of human inhabitation, implicating the risk of human disease due to SLEV infection. Physicians should consider SLEV as a possible aetiology for undiagnosed febrile and neurologic syndromes among their patients who report exposure to mosquito-bites.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 3%
Unknown 56 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 17%
Student > Bachelor 10 17%
Researcher 6 10%
Student > Ph. D. Student 6 10%
Student > Doctoral Student 5 9%
Other 11 19%
Unknown 10 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 28%
Biochemistry, Genetics and Molecular Biology 10 17%
Medicine and Dentistry 6 10%
Immunology and Microbiology 5 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 3 5%
Unknown 16 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 August 2015.
All research outputs
#16,722,913
of 25,377,790 outputs
Outputs from Memórias do Instituto Oswaldo Cruz
#975
of 1,502 outputs
Outputs of similar age
#157,470
of 277,676 outputs
Outputs of similar age from Memórias do Instituto Oswaldo Cruz
#3
of 18 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,502 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,676 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.