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HIGHER VALUES IN LIVER ELASTOGRAPHY AND MELD SCORE ARE MORTALITY PREDICTORS ON LIVER TRANSPLANT WAITING LIST

Overview of attention for article published in ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo), June 2018
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About this Attention Score

  • Among the highest-scoring outputs from this source (#20 of 144)
  • Above-average Attention Score compared to outputs of the same age (59th percentile)

Mentioned by

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1 policy source

Citations

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3 Dimensions

Readers on

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15 Mendeley
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Title
HIGHER VALUES IN LIVER ELASTOGRAPHY AND MELD SCORE ARE MORTALITY PREDICTORS ON LIVER TRANSPLANT WAITING LIST
Published in
ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo), June 2018
DOI 10.1590/0102-672020180001e1360
Pubmed ID
Authors

Lucas Souto NACIF, Denise C PARANAGUA-VEZOZZO, Alina MATSUDA, Venancio Avancini Ferreira ALVES, Flair J CARRILHO, Alberto Queiroz FARIAS, Luiz Carneiro D’ALBUQUERQUE, Wellington ANDRAUS

Abstract

Liver elastography have been reported in hepatocellular carcinoma (HCC) with higher values; however, it is unclear to identify morbimortality risk on liver transplantation waiting list. To assess liver stiffness, ultrasound and clinical findings in cirrhotic patients with and without HCC on screening for liver transplant and compare the morbimortality risk with elastography and MELD score. Patients with cirrhosis and HCC on screening for liver transplant were enrolled with clinical, radiological and laboratory assessments, and transient elastography. 103 patients were included (without HCC n=58 (66%); HCC n=45 (44%). The mean MELD score was 14.7±6.4, the portal hypertension present on 83.9% and the mean transient elastography value was 32.73±22.5 kPa. The median acoustic radiation force impulse value of liver parenchyma was 1.98 (0.65-3.2) m/s and 2.16 (0.59-2.8) m/s in HCC group. The HCC group was significantly associated with HCV infection (OR 26.84; p<0.0001), higher levels of serum alpha-fetoprotein (OR 5.51; p=0.015), clinical portal hypertension (OR 0.25; p=0.032) and similar MELD score (p=0.693). The area under the receiver operating characteristics (AUROC) showed sensitivity and specificity for serum alpha-fetoprotein (cutoff 9.1 ng/ml), transient elastography value (cutoff value 9 kPa), and acoustic radiation force impulse value (cutoff value 2.56 m/s) of 50% and 86%, 92% and 17% and 21% and 92%, respectively. The survival group had a mean transient elastography value of 31.65±22.2 kPa vs. 50.87±20.9 kPa (p=0.098) and higher MELD scores (p=0.035). Elastography, ultrasound and clinical findings are important non-invasive tools for cirrhosis and HCC on screening for liver transplant. Higher values in liver elastography and MELD scores predict mortality.

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 27%
Researcher 2 13%
Lecturer 1 7%
Professor 1 7%
Student > Doctoral Student 1 7%
Other 2 13%
Unknown 4 27%
Readers by discipline Count As %
Medicine and Dentistry 7 47%
Nursing and Health Professions 2 13%
Pharmacology, Toxicology and Pharmaceutical Science 1 7%
Unknown 5 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2019.
All research outputs
#5,242,255
of 16,450,433 outputs
Outputs from ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)
#20
of 144 outputs
Outputs of similar age
#108,656
of 280,909 outputs
Outputs of similar age from ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)
#1
of 3 outputs
Altmetric has tracked 16,450,433 research outputs across all sources so far. This one is in the 48th percentile – i.e., 48% of other outputs scored the same or lower than it.
So far Altmetric has tracked 144 research outputs from this source. They receive a mean Attention Score of 1.6. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,909 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them