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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The effects of probiotic supplementation on metabolic status in type 2 diabetic patients with coronary heart disease
|
|---|---|
| Published in |
Diabetology & Metabolic Syndrome, June 2018
|
| DOI | 10.1186/s13098-018-0353-2 |
| Pubmed ID | |
| Authors |
Fariba Raygan, Zohreh Rezavandi, Fereshteh Bahmani, Vahidreza Ostadmohammadi, Mohammad Ali Mansournia, Maryam Tajabadi-Ebrahimi, Shokoofeh Borzabadi, Zatollah Asemi |
| Abstract |
This study was conducted to evaluate the effects of probiotic supplementation on metabolic profiles in diabetic patients with coronary heart disease (CHD). This randomized, double-blind, placebo-controlled trial was performed among 60 diabetic patients with CHD, aged 40-85 years at a cardiology clinic in Kashan, Iran, from October 2017 through January 2018. Patients were randomly divided into two groups to take either probiotic supplements (n = 30) or placebo (n = 30) for 12 weeks. Fasting blood samples were taken at the beginning of the study and after the 12-week intervention to determine related markers. After 12-week intervention, probiotic supplementation significantly decreased fasting plasma glucose (β - 20.02 mg/dL; 95% CI - 33.86, - 6.17; P = 0.005), insulin (β - 2.09 µIU/mL; 95% CI - 3.77, - 0.41; P = 0.01), insulin resistance (β - 0.50; 95% CI - 0.96, - 0.03; P = 0.03) and total-/HDL-cholesterol ratio (β - 0.27; 95% CI - 0.52, - 0.03; P = 0.02), and significantly increased insulin sensitivity (β 0.008; 95% CI 0.001, 0.01; P = 0.02) and HDL-cholesterol levels (β 2.52 mg/dL; 95% CI 0.04, 5.00; P = 0.04) compared with the placebo. Moreover, probiotic supplementation led to a significant reduction in serum high sensitivity C-reactive protein (β - 0.88 mg/L; 95% CI - 1.39, - 0.38; P = 0.001), and a significant elevation in total antioxidant capacity (β 108.44 mmol/L; 95% CI 47.61, 169.27; P = 0.001) and total glutathione levels (β 45.15 µmol/L; 95% CI 5.82, 84.47; P = 0.02) compared with the placebo. Probiotic supplementation did not affect other metabolic profiles. Overall, we found that probiotic supplementation for 12 weeks had beneficial effects on glycemic control, HDL-cholesterol, total-/HDL-cholesterol ratio, biomarkers of inflammation and oxidative stress in diabetic patients with CHD.Trial registration Clinical trial registration number http://www.irct.ir: IRCT2017082733941N5. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 124 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 21 | 17% |
| Student > Ph. D. Student | 14 | 11% |
| Researcher | 10 | 8% |
| Student > Doctoral Student | 9 | 7% |
| Student > Master | 6 | 5% |
| Other | 13 | 10% |
| Unknown | 51 | 41% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 25 | 20% |
| Nursing and Health Professions | 14 | 11% |
| Agricultural and Biological Sciences | 8 | 6% |
| Biochemistry, Genetics and Molecular Biology | 7 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 3% |
| Other | 8 | 6% |
| Unknown | 58 | 47% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 November 2018.
All research outputs
#14,418,409
of 23,092,602 outputs
Outputs from Diabetology & Metabolic Syndrome
#324
of 678 outputs
Outputs of similar age
#185,289
of 328,045 outputs
Outputs of similar age from Diabetology & Metabolic Syndrome
#3
of 10 outputs
Altmetric has tracked 23,092,602 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 678 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,045 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.