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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers
|
|---|---|
| Published in |
Fluids and Barriers of the CNS, July 2018
|
| DOI | 10.1186/s12987-018-0104-7 |
| Pubmed ID | |
| Authors |
Servio H. Ramirez, Allison M. Andrews, Debayon Paul, Joel S. Pachter |
| Abstract |
Extracellular vesicles (EVs) are heterogeneous, nano-sized vesicles that are shed into the blood and other body fluids, which disperse a variety of bioactive molecules (e.g., protein, mRNA, miRNA, DNA and lipids) to cellular targets over long and short distances. EVs are thought to be produced by nearly every cell type, however this review will focus specifically on EVs that originate from cells at the interface of CNS barriers. Highlighted topics include, EV biogenesis, the production of EVs in response to neuroinflammation, role in intercellular communication and their utility as a therapeutic platform. In this review, novel concepts regarding the use of EVs as biomarkers for BBB status and as facilitators for immune neuroinvasion are also discussed. Future directions and prospective are covered along with important unanswered questions in the field of CNS endothelial EV biology. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Finland | 1 | 13% |
| United Kingdom | 1 | 13% |
| United States | 1 | 13% |
| Unknown | 5 | 63% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 63% |
| Scientists | 3 | 38% |
Mendeley readers
The data shown below were compiled from readership statistics for 178 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 178 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 27 | 15% |
| Student > Ph. D. Student | 25 | 14% |
| Student > Master | 22 | 12% |
| Researcher | 20 | 11% |
| Other | 13 | 7% |
| Other | 28 | 16% |
| Unknown | 43 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 35 | 20% |
| Neuroscience | 25 | 14% |
| Medicine and Dentistry | 21 | 12% |
| Agricultural and Biological Sciences | 13 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 4% |
| Other | 22 | 12% |
| Unknown | 55 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 November 2018.
All research outputs
#6,410,186
of 24,909,203 outputs
Outputs from Fluids and Barriers of the CNS
#129
of 433 outputs
Outputs of similar age
#102,203
of 334,082 outputs
Outputs of similar age from Fluids and Barriers of the CNS
#2
of 4 outputs
Altmetric has tracked 24,909,203 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 433 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 334,082 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.