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Comprehensive pharmaceutical care to prevent drug-related readmissions of dependent-living elderly patients: a randomized controlled trial

Overview of attention for article published in BMC Geriatrics, June 2018
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  • Above-average Attention Score compared to outputs of the same age (61st percentile)

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Title
Comprehensive pharmaceutical care to prevent drug-related readmissions of dependent-living elderly patients: a randomized controlled trial
Published in
BMC Geriatrics, June 2018
DOI 10.1186/s12877-018-0814-3
Pubmed ID
Authors

R. Lenssen, K. Schmitz, C. Griesel, A. Heidenreich, J. B. Schulz, C. Trautwein, N. Marx, C. Fitzner, U. Jaehde, A. Eisert

Abstract

Elderly patients are vulnerable to adverse drug reactions (ADRs). Drug-related readmissions (DRRs) can be a major consequence of ADR. Therefore, this study aimed to investigate the effects of a ward-based, comprehensive pharmaceutical care service on the occurrence of DRRs as the endpoint in dependent-living elderly patients. A randomized, controlled trial was performed at a German University Hospital. Patients fulfilling the following criteria were eligible: admission to a cooperating ward, existing drug therapy at admission, 65 years of age and older, home-care or nursing home residents in ambulatory care, and a minimum hospital stay of three days. Patients received either standard care (control group) or pharmaceutical care (intervention group). Follow-up consultations were conducted for each patient at 1, 8, 26, and 52 weeks after discharge. The time to DRR was defined as the primary outcome measure and was analysed using the log-rank test. The Cox-proportional hazard model was used for risk factor analysis. Sixty patients (n = 31 intervention group, n = 29 control group) participated in the study. For patients in the intervention group, the median time to DRR was prolonged; however, the level of statistical significance was not reached (log-rank test P = 0.068; HR = 3.28, P = 0.086). When the risk factors 'age' or 'length of stay on the ward' were added to the Cox proportional hazard model, patients in the control group exhibited a significantly higher risk of experiencing a DRR than patients of the intervention group (HR = 4.62; P = 0.028 including age and HR = 5.76; P = 0.033 including length of stay on the ward). Our findings demonstrate the successful implementation of ward-based, comprehensive pharmaceutical care for dependent-living elderly. Despite a low participation rate, which led to an underpowered study, the results provide a preliminary efficacy signal and effect size estimates to power a definitive trial. Clinicaltrials.gov identifier: NCT01578525 , prospectively registered April 13, 2012.

X Demographics

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The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 131 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 131 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 18 14%
Student > Bachelor 13 10%
Researcher 10 8%
Student > Ph. D. Student 10 8%
Other 9 7%
Other 24 18%
Unknown 47 36%
Readers by discipline Count As %
Medicine and Dentistry 24 18%
Pharmacology, Toxicology and Pharmaceutical Science 23 18%
Nursing and Health Professions 15 11%
Biochemistry, Genetics and Molecular Biology 3 2%
Arts and Humanities 3 2%
Other 12 9%
Unknown 51 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 July 2018.
All research outputs
#7,256,451
of 23,094,276 outputs
Outputs from BMC Geriatrics
#1,724
of 3,261 outputs
Outputs of similar age
#125,228
of 329,888 outputs
Outputs of similar age from BMC Geriatrics
#44
of 56 outputs
Altmetric has tracked 23,094,276 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 3,261 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,888 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.