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Total Synthesis of (−)-Conolutinine

Overview of attention for article published in Organic Letters, August 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

blogs
1 blog
twitter
7 tweeters

Citations

dimensions_citation
16 Dimensions

Readers on

mendeley
31 Mendeley
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Title
Total Synthesis of (−)-Conolutinine
Published in
Organic Letters, August 2015
DOI 10.1021/acs.orglett.5b02046
Pubmed ID
Authors

Xiangyang Feng, Guangde Jiang, Zilei Xia, Jiadong Hu, Xiaolong Wan, Jin-Ming Gao, Yisheng Lai, Weiqing Xie

Abstract

The first enantioselective synthesis of (-)-conolutinine was achieved in 10 steps. The synthesis featured a catalytic asymmetric bromocyclization of tryptamine to forge the tricycle intermediate. Hydration of an alkene catalyzed by Co(acac)2 was also employed as a key step to diastereoselectively introduce the tertiary alcohol moiety. The absolute configuration of (-)-conolutinine was established to be (2S,5aS,8aS,13aR) based on this asymmetric total synthesis.

Twitter Demographics

The data shown below were collected from the profiles of 7 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
United States 1 3%
Unknown 29 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 23%
Student > Ph. D. Student 6 19%
Student > Master 6 19%
Student > Doctoral Student 3 10%
Professor > Associate Professor 3 10%
Other 5 16%
Unknown 1 3%
Readers by discipline Count As %
Chemistry 23 74%
Chemical Engineering 3 10%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Medicine and Dentistry 1 3%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 0 0%
Unknown 2 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 October 2015.
All research outputs
#1,017,879
of 12,308,537 outputs
Outputs from Organic Letters
#173
of 8,738 outputs
Outputs of similar age
#28,315
of 244,749 outputs
Outputs of similar age from Organic Letters
#4
of 160 outputs
Altmetric has tracked 12,308,537 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,738 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,749 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 160 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.