Title |
Plasmodium and intestinal parasite perturbations of the infected host’s inflammatory responses: a systematic review
|
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Published in |
Parasites & Vectors, July 2018
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DOI | 10.1186/s13071-018-2948-8 |
Pubmed ID | |
Authors |
Aminata Colle Lo, Babacar Faye, Ben Adu Gyan, Linda Eva Amoah |
Abstract |
Co-infection of malaria and intestinal parasites is widespread in sub-Saharan Africa and causes severe disease especially among the poorest populations. It has been shown that an intestinal parasite (helminth), mixed intestinal helminth or Plasmodium parasite infection in a human induces a wide range of cytokine responses, including anti-inflammatory, pro-inflammatory as well as regulatory cytokines. Although immunological interactions have been suggested to occur during a concurrent infection of helminths and Plasmodium parasites, different conclusions have been drawn on the influence this co-infection has on cytokine production. This review briefly discusses patterns of selected cytokine (IL-6, IL-8, IL-10, TNF-α and INF-γ) responses associated with infections caused by Plasmodium, intestinal parasites as well as a Plasmodium-helminth co-infection. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 22% |
Senegal | 1 | 11% |
Mali | 1 | 11% |
Chile | 1 | 11% |
United Kingdom | 1 | 11% |
Unknown | 3 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 78% |
Science communicators (journalists, bloggers, editors) | 1 | 11% |
Scientists | 1 | 11% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 64 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 15 | 23% |
Researcher | 9 | 14% |
Student > Ph. D. Student | 7 | 11% |
Student > Postgraduate | 5 | 8% |
Lecturer | 3 | 5% |
Other | 5 | 8% |
Unknown | 20 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 10 | 16% |
Medicine and Dentistry | 10 | 16% |
Immunology and Microbiology | 7 | 11% |
Biochemistry, Genetics and Molecular Biology | 4 | 6% |
Nursing and Health Professions | 2 | 3% |
Other | 9 | 14% |
Unknown | 22 | 34% |