Title |
ROLE OF PARENTERAL NUTRITION IN ONCOLOGIC PATIENTS WITH INTESTINAL OCCLUSION AND PERITONEAL CARCINOMATOSIS.
|
---|---|
Published in |
Nutricion Hospitalaria, January 2015
|
DOI | 10.3305/nh.2015.32.3.9184 |
Pubmed ID | |
Authors |
Aría Guerra, Eva, Cortés-Salgado, Alfonso, Mateo-Lobo, Raquel, Nattero, Lía, Riveiro, Javier, Vega-Piñero, Belén, Valbuena, Beatriz, Carabaña, Fátima, Carrero, Carmen, Grande, Enrique, Carrato, Alfredo, Botella-Carretero, José Ignacio |
Abstract |
the precise role of parenteral nutrition in the management of oncologic patients with intestinal occlusion is not well defined yet. We aimed to identify the effects of parenteral nutrition in these patients regarding prognosis. 55 patients with intestinal occlusion and peritoneal carcinomatosis were included. Parenteral nutrition aimed at 20-35 kcal/Kg/day, and 1.0 g/kg/day of amino-acids. Weight, body mass index, type of tumor, type of chemotherapy, and ECOG among others were recorded and analyzed. 69.1% of the patients had gastrointestinal tumors, 18.2% gynecologic and 12.7% others. Age was 60 ± 13y, baseline ECOG 1.5 ± 0.5 and body mass index 21.6 ± 4.3. Malnutrition was present in 85%. Survival from the start of parenteral nutrition was not significant when considering baseline ECOG (log rank = 0.593, p = 0.743), previous lines of chemotherapy (log rank = 2.117, p = 0.548), baseline BMI (log rank = 2.686, p = 0.261), or type of tumor (log rank = 2.066, p = 0.356). Survival in patients who received home parenteral nutrition after hospital discharge was higher than those who stayed in-hospital (log rank = 7.090, p = 0.008). Survival in patients who started chemotherapy during or after parenteral nutrition was higher than those who did not so (log rank = 17.316, p < 0.001). A total of 3.6% of patients presented catheter related infection without affecting survival (log rank = 0.061, p = 0.804). Parenteral nutrition in patients with advanced cancer and intestinal occlusion is safe, and in tho se who respond to chemotherapy, further administration of home parenteral nutrition together with chemotherapy may enhance prolonged survival. |
Twitter Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 32 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 6 | 19% |
Other | 3 | 9% |
Student > Doctoral Student | 3 | 9% |
Student > Bachelor | 3 | 9% |
Student > Master | 3 | 9% |
Other | 7 | 22% |
Unknown | 7 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 41% |
Nursing and Health Professions | 7 | 22% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Business, Management and Accounting | 1 | 3% |
Other | 2 | 6% |
Unknown | 7 | 22% |