Prion2019 Day 1: Biomarker Workshop
CureFFI.org,
We are in Edmonton, Alberta for the Prion2019 conference attending the afternoon Biomarker Workshop hosted by Kurt Giles
Protein Misfolding Diseases
Overview of attention for book
Table of Contents
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Altmetric BadgeBook Overview
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Altmetric BadgeChapter 1 Biophysical and Spectroscopic Methods for Monitoring Protein Misfolding and Amyloid Aggregation
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Altmetric BadgeChapter 2 Ultrasensitive RT-QuIC Seed Amplification Assays for Disease-Associated Tau, α-Synuclein, and Prion Aggregates
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Altmetric BadgeChapter 3 Vesicle-Based Assays to Study Membrane Interactions of Amyloid Peptides
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Altmetric BadgeChapter 4 Differential Scanning Fluorimetry and Hydrogen Deuterium Exchange Mass Spectrometry to Monitor the Conformational Dynamics of NBD1 in Cystic Fibrosis
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Altmetric BadgeChapter 5 A Multipronged Method for Unveiling Subtle Structural–Functional Defects of Mutant Chaperone Molecules Causing Human Chaperonopathies
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Altmetric BadgeChapter 6 High-Throughput Microplate-Based Fluorescence Assays for Studying Stochastic Aggregation of Superoxide Dismutase-1
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Altmetric BadgeChapter 7 Methods for Structural Analysis of Amyloid Fibrils in Misfolding Diseases
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Altmetric BadgeChapter 8 Assays for Light Chain Amyloidosis Formation and Cytotoxicity
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Altmetric BadgeChapter 9 Monitoring Aggregate Clearance and Formation in Cell-Based Assays
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Altmetric BadgeChapter 10 Monitoring Proteome Stress in Live Cells Using HaloTag-Based Fluorogenic Sensor
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Altmetric BadgeChapter 11 Quantification of Protein Aggregates Using Bimolecular Fluorescence Complementation
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Altmetric BadgeChapter 12 Screening Protein Aggregation in Cells Using Fluorescent Labels Coupled to Flow Cytometry
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Altmetric BadgeChapter 13 Induction of Cu/Zn Superoxide Dismutase (SOD1) Aggregation in Living Cells
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Altmetric BadgeChapter 14 A Cell Model for HSP60 Deficiencies: Modeling Different Levels of Chaperonopathies Leading to Oxidative Stress and Mitochondrial Dysfunction
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Altmetric BadgeChapter 15 Superresolution Fluorescence Imaging of Mutant Huntingtin Aggregation in Cells
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Altmetric BadgeChapter 16 Thermal Shift and Stability Assays of Disease-Related Misfolded Proteins Using Differential Scanning Fluorimetry
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Altmetric BadgeChapter 17 Methods to Screen Compounds Against Mutant p53 Misfolding and Aggregation for Cancer Therapeutics
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Altmetric BadgeChapter 18 Early Stage Discovery and Validation of Pharmacological Chaperones for the Correction of Protein Misfolding Diseases
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Altmetric BadgeChapter 19 Constructing Kinetically Controlled Denaturation Isotherms of Folded Proteins Using Denaturant-Pulse Chaperonin Binding
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Altmetric BadgeChapter 20 In Vitro Prion Amplification Methodology for Inhibitor Screening
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Altmetric BadgeChapter 21 SolubiS: Optimizing Protein Solubility by Minimal Point Mutations