↓ Skip to main content

Glycemic dysregulation in a patient with type 2 diabetes treated with 5-azacitidine: a case report

Overview of attention for article published in Journal of Medical Case Reports, July 2018
Altmetric Badge

Mentioned by

twitter
2 tweeters

Citations

dimensions_citation
4 Dimensions

Readers on

mendeley
15 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Glycemic dysregulation in a patient with type 2 diabetes treated with 5-azacitidine: a case report
Published in
Journal of Medical Case Reports, July 2018
DOI 10.1186/s13256-018-1690-3
Pubmed ID
Authors

Antoine Ponard, Nicole Ferreira-Maldent, Marjan Ertault, Martine Delain, Kamel Amraoui, Sandra Regina, Annie-Pierre Jonville-Béra, Olivier Hérault, Philippe Colombat, Emmanuel Gyan

Abstract

Diabetes and myelodysplastic syndrome are two conditions that may coexist in a single patient, since both diseases are prevalent in the elderly. The pathophysiology of myelodysplastic syndrome involves recurrent genetic mutations, especially in genes controlling epigenetic regulation. Although the pathophysiology of diabetes is not well understood, several studies suggest a role of epigenetics in type 2 diabetes. We report here for the first time the case of a 75-year-old Caucasian man who was treated for both diabetes and acute myeloid leukemia secondary to myelodysplastic syndrome, with a temporal association between glycemic dysregulation and the intake of 5-azacitidine. In fact, 2-3 days after starting each 7-day cycle of 5-azacitidine, he reported higher blood glucose levels, requiring an increased dose of self-administered insulin. This observation could help to understand the pathophysiology of these two conditions and could encourage physicians to monitor blood glucose levels in patients under hypomethylating agent with a history of diabetes.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 27%
Student > Ph. D. Student 3 20%
Student > Bachelor 3 20%
Professor 2 13%
Other 1 7%
Other 1 7%
Unknown 1 7%
Readers by discipline Count As %
Medicine and Dentistry 8 53%
Biochemistry, Genetics and Molecular Biology 2 13%
Agricultural and Biological Sciences 1 7%
Decision Sciences 1 7%
Pharmacology, Toxicology and Pharmaceutical Science 1 7%
Other 0 0%
Unknown 2 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 November 2020.
All research outputs
#15,466,334
of 19,311,167 outputs
Outputs from Journal of Medical Case Reports
#1,730
of 3,287 outputs
Outputs of similar age
#217,906
of 288,791 outputs
Outputs of similar age from Journal of Medical Case Reports
#1
of 1 outputs
Altmetric has tracked 19,311,167 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,287 research outputs from this source. They receive a mean Attention Score of 3.1. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,791 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them