Title |
The role of microRNAs in enteroviral infections
|
---|---|
Published in |
Brazilian Journal of Infectious Diseases, September 2015
|
DOI | 10.1016/j.bjid.2015.06.011 |
Pubmed ID | |
Authors |
Jing Wu, Li Shen, Jianguo Chen, Huaxi Xu, Lingxiang Mao |
Abstract |
The genus Enterovirus, a member of the Picornavirus family, are RNA viruses that can cause poliomyelitis, hand-food-mouth disease, viral meningitis or meningoencephalitis, viral myocarditis and so on. MicroRNAs are a class of highly conserved, small noncoding RNAs recognized as important regulators of gene expression. Recent studies found that MicroRNAs play a significant role in the infection of Enterovirus, such as enterovirus 71, coxsackievirus B3 and other Enterovirus. Enteroviral infection can alter the expression of cellular MicroRNAs, and cellular MicroRNAs can modulate viral pathogenesis and replication by regulating the expression level of viral or host's genes. Herein, this review summarizes the role of MicroRNAs in enteroviral infection. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 33 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 30% |
Student > Master | 4 | 12% |
Student > Bachelor | 3 | 9% |
Student > Postgraduate | 3 | 9% |
Other | 2 | 6% |
Other | 5 | 15% |
Unknown | 6 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 27% |
Biochemistry, Genetics and Molecular Biology | 7 | 21% |
Agricultural and Biological Sciences | 3 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
Veterinary Science and Veterinary Medicine | 2 | 6% |
Other | 3 | 9% |
Unknown | 7 | 21% |