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Follistatin-like 1 in vertebrate development.

Overview of attention for article published in Birth Defects Research Part C: Embryo Today: Reviews, March 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (68th percentile)

Mentioned by

wikipedia
1 Wikipedia page

Citations

dimensions_citation
27 Dimensions

Readers on

mendeley
20 Mendeley
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Title
Follistatin-like 1 in vertebrate development.
Published in
Birth Defects Research Part C: Embryo Today: Reviews, March 2013
DOI 10.1002/bdrc.21030
Pubmed ID
Authors

Sylva, M., Moorman, A.F.M., Hoff, M.J.B.

Abstract

Follistatin-like 1 (Fstl1) is a member of the secreted protein acidic rich in cysteins (SPARC) family and has been implicated in many different signaling pathways, including bone morphogenetic protein (BMP) signaling. In many different developmental processes like, dorso-ventral axis establishment, skeletal, lung and ureter development, loss of function experiments have unveiled an important role for Fstl1. Fstl1 largely functions through inhibiting interactions with the BMP signaling pathway, although, in various disease models, different signaling pathways, like activation of pAKT, pAMPK, Na/K-ATPase, or innate immune responses, are linked to Fstl1. How Fstl1 inhibits BMP signaling remains unclear, although it is known that Fstl1 does not function through a scavenging mechanism, like the other known extracellular BMP inhibitors such as noggin. It has been proposed that Fstl1 interferes with BMP receptor complex formation and as such inhibits propagation of the BMP signal into the cell. Future challenges will encompass the identification of the factors that determine the mechanisms that underlie the fact that Fstl1 acts by interfering with BMP signaling during development, but through other signaling pathways during disease.

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 30%
Student > Ph. D. Student 5 25%
Professor 3 15%
Student > Master 2 10%
Student > Doctoral Student 1 5%
Other 3 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 45%
Biochemistry, Genetics and Molecular Biology 6 30%
Medicine and Dentistry 3 15%
Unspecified 1 5%
Neuroscience 1 5%
Other 0 0%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 August 2015.
All research outputs
#1,399,417
of 5,573,505 outputs
Outputs from Birth Defects Research Part C: Embryo Today: Reviews
#19
of 94 outputs
Outputs of similar age
#59,765
of 193,742 outputs
Outputs of similar age from Birth Defects Research Part C: Embryo Today: Reviews
#1
of 3 outputs
Altmetric has tracked 5,573,505 research outputs across all sources so far. This one has received more attention than most of these and is in the 63rd percentile.
So far Altmetric has tracked 94 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 193,742 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them