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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A legion of potential regulatory sRNAs exists beyond the typical microRNAs microcosm
|
|---|---|
| Published in |
Nucleic Acids Research, September 2015
|
| DOI | 10.1093/nar/gkv871 |
| Pubmed ID | |
| Authors |
Ashwani Jha, Ganesh Panzade, Rajesh Pandey, Ravi Shankar |
| Abstract |
Post ENCODE, regulatory sRNAs (rsRNAs) like miRNAs have established their status as one of the core regulatory elements of cell systems. However, large number of rsRNAs are compromised due to traditional approaches to identify miRNAs, limiting the otherwise vast world of rsRNAs mainly to hair-pin loop bred typical miRNAs. The present study has analyzed for the first time a huge volume of sequencing data from 4997 individuals and 25 cancer types to report 11 234 potentially regulatory small RNAs which appear to have deep reaching impact. The rsRNA-target interactions have been studied and validated extensively using experimental data from AGO-crosslinking, DGCR8 knockdown, CLASH, proteome and expression data. A subset of such interactions was also validated independently in the present study using multiple cell lines, by qPCR. Several of the potential rsRNAs have emerged as a critical cancer biomarker controlling some important spots of cell system. The entire study has been presented into an interactive info-analysis portal handling more than 260 GB of processed data. The possible degree of cell system regulation by sRNAs appears to be much higher than previously assumed. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 43% |
| India | 1 | 14% |
| Canada | 1 | 14% |
| Australia | 1 | 14% |
| Unknown | 1 | 14% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 57% |
| Scientists | 3 | 43% |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| South Africa | 1 | 2% |
| Czechia | 1 | 2% |
| Belgium | 1 | 2% |
| Denmark | 1 | 2% |
| United States | 1 | 2% |
| Unknown | 36 | 88% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 15 | 37% |
| Student > Ph. D. Student | 10 | 24% |
| Student > Master | 5 | 12% |
| Student > Doctoral Student | 2 | 5% |
| Student > Bachelor | 2 | 5% |
| Other | 7 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 14 | 34% |
| Biochemistry, Genetics and Molecular Biology | 13 | 32% |
| Computer Science | 5 | 12% |
| Medicine and Dentistry | 2 | 5% |
| Environmental Science | 1 | 2% |
| Other | 2 | 5% |
| Unknown | 4 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 May 2016.
All research outputs
#2,712,086
of 23,577,761 outputs
Outputs from Nucleic Acids Research
#3,499
of 26,683 outputs
Outputs of similar age
#36,639
of 268,679 outputs
Outputs of similar age from Nucleic Acids Research
#47
of 300 outputs
Altmetric has tracked 23,577,761 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 26,683 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,679 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 300 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.