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X Demographics
Mendeley readers
Attention Score in Context
| Title |
DNA methylation landscapes in the pathogenesis of type 2 diabetes mellitus
|
|---|---|
| Published in |
Nutrition & Metabolism, June 2018
|
| DOI | 10.1186/s12986-018-0283-x |
| Pubmed ID | |
| Authors |
Zheng Zhou, Bao Sun, Xiaoping Li, Chunsheng Zhu |
| Abstract |
Although genetic variations and environmental factors are vital to the development and progression of type 2 diabetes mellitus (T2DM), emerging literature suggest that epigenetics, especially DNA methylation, play a key role in the pathogenesis of T2DM by affecting insulin secretion of pancreatic β cells and the body's resistance to insulin. Previous studies have elucidated how DNA methylation interacted with various factors in T2DM pathogenesis. This review summarized the role of related methylation genes in insulin-sensitive organs, such as pancreatic islets, skeletal muscle, liver, brain and adipose tissue, as well as peripheral blood cells, comparing the tissue similarity and specificity of methylated genes, aiming at a better understanding of the pathogenesis of T2DM and providing new ideas for the personalized treatment of this metabolism-associated disease. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 92 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 18 | 20% |
| Student > Master | 13 | 14% |
| Researcher | 5 | 5% |
| Lecturer | 5 | 5% |
| Student > Doctoral Student | 5 | 5% |
| Other | 16 | 17% |
| Unknown | 30 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 18 | 20% |
| Medicine and Dentistry | 10 | 11% |
| Nursing and Health Professions | 9 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 8% |
| Agricultural and Biological Sciences | 7 | 8% |
| Other | 7 | 8% |
| Unknown | 34 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2020.
All research outputs
#6,380,577
of 23,096,849 outputs
Outputs from Nutrition & Metabolism
#429
of 952 outputs
Outputs of similar age
#111,023
of 329,256 outputs
Outputs of similar age from Nutrition & Metabolism
#8
of 16 outputs
Altmetric has tracked 23,096,849 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 952 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.7. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,256 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.