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Validation of ethnopharmacological uses of Murraya paniculata in disorders of diarrhea, asthma and hypertension

Overview of attention for article published in BMC Complementary Medicine and Therapies, September 2015
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Title
Validation of ethnopharmacological uses of Murraya paniculata in disorders of diarrhea, asthma and hypertension
Published in
BMC Complementary Medicine and Therapies, September 2015
DOI 10.1186/s12906-015-0837-7
Pubmed ID
Authors

Fatima Saqib, Mobeen Ghulam Ahmed, Khalid Hussain Janbaz, Saikat Dewanjee, Hawa ZE Jaafar, Muhammad Zia-Ul-Haq

Abstract

Murraya paniculata is traditionally used for management of gut, air way and cardiovascular disorders. The study was conducted for provision of pharmacological rationalization for folkloric uses of Murraya paniculata in gut, air way and cardiovascular problems. Aqueous-ethanolic extract of Mp.Cr was tested using in vitro techniques on isolated tissue of rabbit (jejunum, trachea and aorta) to detect the possible presence of spasmolytic activity. The responses of tissues were recorded using isotonic transducers coupled with PowerLab data acquisition system. Application of the extract of Mp.Cr relaxed spontaneous and high K(+) (80mM)-induced contraction in rabbit jejunum preparation. Because it shifted the CRCs (Calcium response curve) towards the right side so the possible blockade was of calcium channel similar to verapamil. In rabbit trachea, extract of Mp.Cr produced relaxation of carbachol and high K(+) induced contractions. When plant extract was checked further on isolated aorta for its possible vasodilator effect, it caused relaxation of phenylephrine and high K(+)-induced spastic contractions at different doses. These results indicate that Murraya paniculata shows anti-spasmodic, bronchodilator and vasodilator activity facilitated through Ca(++) antagonist mechanisms.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iran, Islamic Republic of 1 2%
Unknown 56 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 14%
Student > Ph. D. Student 7 12%
Researcher 3 5%
Professor 3 5%
Lecturer 3 5%
Other 9 16%
Unknown 24 42%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 9 16%
Medicine and Dentistry 6 11%
Chemistry 4 7%
Agricultural and Biological Sciences 3 5%
Biochemistry, Genetics and Molecular Biology 3 5%
Other 4 7%
Unknown 28 49%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 March 2016.
All research outputs
#15,346,908
of 22,828,180 outputs
Outputs from BMC Complementary Medicine and Therapies
#2,045
of 3,631 outputs
Outputs of similar age
#156,594
of 267,220 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#48
of 87 outputs
Altmetric has tracked 22,828,180 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,631 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 267,220 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.