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Validation of ethnopharmacological uses of Murraya paniculata in disorders of diarrhea, asthma and hypertension

Overview of attention for article published in BMC Complementary and Alternative Medicine, September 2015
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Title
Validation of ethnopharmacological uses of Murraya paniculata in disorders of diarrhea, asthma and hypertension
Published in
BMC Complementary and Alternative Medicine, September 2015
DOI 10.1186/s12906-015-0837-7
Pubmed ID
Authors

Fatima Saqib, Mobeen Ghulam Ahmed, Khalid Hussain Janbaz, Saikat Dewanjee, Hawa ZE Jaafar, Muhammad Zia-Ul-Haq

Abstract

Murraya paniculata is traditionally used for management of gut, air way and cardiovascular disorders. The study was conducted for provision of pharmacological rationalization for folkloric uses of Murraya paniculata in gut, air way and cardiovascular problems. Aqueous-ethanolic extract of Mp.Cr was tested using in vitro techniques on isolated tissue of rabbit (jejunum, trachea and aorta) to detect the possible presence of spasmolytic activity. The responses of tissues were recorded using isotonic transducers coupled with PowerLab data acquisition system. Application of the extract of Mp.Cr relaxed spontaneous and high K(+) (80mM)-induced contraction in rabbit jejunum preparation. Because it shifted the CRCs (Calcium response curve) towards the right side so the possible blockade was of calcium channel similar to verapamil. In rabbit trachea, extract of Mp.Cr produced relaxation of carbachol and high K(+) induced contractions. When plant extract was checked further on isolated aorta for its possible vasodilator effect, it caused relaxation of phenylephrine and high K(+)-induced spastic contractions at different doses. These results indicate that Murraya paniculata shows anti-spasmodic, bronchodilator and vasodilator activity facilitated through Ca(++) antagonist mechanisms.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iran, Islamic Republic of 1 2%
Unknown 41 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 19%
Student > Ph. D. Student 5 12%
Researcher 3 7%
Student > Master 3 7%
Lecturer 2 5%
Other 5 12%
Unknown 16 38%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 7 17%
Medicine and Dentistry 6 14%
Biochemistry, Genetics and Molecular Biology 2 5%
Nursing and Health Professions 2 5%
Agricultural and Biological Sciences 2 5%
Other 4 10%
Unknown 19 45%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 March 2016.
All research outputs
#5,626,745
of 7,435,912 outputs
Outputs from BMC Complementary and Alternative Medicine
#1,343
of 1,832 outputs
Outputs of similar age
#156,993
of 227,869 outputs
Outputs of similar age from BMC Complementary and Alternative Medicine
#53
of 74 outputs
Altmetric has tracked 7,435,912 research outputs across all sources so far. This one is in the 13th percentile – i.e., 13% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,832 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,869 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.