RT @bmj_company: A reanalysis of #Study329 found #paroxetine to be ineffective & unsafe https://t.co/k4dKfjTapY #altmetrictop100 https://t.…
RT @bmj_company: A reanalysis of #Study329 found #paroxetine to be ineffective & unsafe https://t.co/k4dKfjTapY #altmetrictop100 https://t.…
RT @DrEvgenyLegedin: #Study329 is a case of scientifuc fraud in psychiatry. GlaxoSmithKline hid the suicidal events in the group of teenag…
RT @DrEvgenyLegedin: #Study329 is a case of scientifuc fraud in psychiatry. GlaxoSmithKline hid the suicidal events in the group of teenag…
RT @DrEvgenyLegedin: #Study329 is a case of scientifuc fraud in psychiatry. GlaxoSmithKline hid the suicidal events in the group of teenag…
RT @DrEvgenyLegedin: #Study329 is a case of scientifuc fraud in psychiatry. GlaxoSmithKline hid the suicidal events in the group of teenag…
RT @DrEvgenyLegedin: #Study329 is a case of scientifuc fraud in psychiatry. GlaxoSmithKline hid the suicidal events in the group of teenag…
RT @DrEvgenyLegedin: #Study329 is a case of scientifuc fraud in psychiatry. GlaxoSmithKline hid the suicidal events in the group of teenag…
RT @DrEvgenyLegedin: In 2003 Britain's Medicines and Healthcare Products Regulatory Agency analysed #Study329 and found 'robust evidence' t…
RT @DrEvgenyLegedin: In 2003 Britain's Medicines and Healthcare Products Regulatory Agency analysed #Study329 and found 'robust evidence' t…
@eisenlohr_moul @AliBeckZeck There is also the PANDA study etc. I will say the studies you post are flawed bias so a waste of time. Maybe professionals need to start looking at what is not working rather than what is? Remember SU also fear psychiatrists
RT @DrEvgenyLegedin: In 2003 Britain's Medicines and Healthcare Products Regulatory Agency analysed #Study329 and found 'robust evidence' t…
RT @DrEvgenyLegedin: In 2003 Britain's Medicines and Healthcare Products Regulatory Agency analysed #Study329 and found 'robust evidence' t…
RT @DrEvgenyLegedin: In 2003 Britain's Medicines and Healthcare Products Regulatory Agency analysed #Study329 and found 'robust evidence' t…
In 2003 Britain's Medicines and Healthcare Products Regulatory Agency analysed #Study329 and found 'robust evidence' that paroxetine causes suicidal behaviour in teenagers. MHRA launched a criminal inquiry into GSK's conduct, but announced in 2008 that the
RT @DrEvgenyLegedin: #Study329 is a case of scientifuc fraud in psychiatry. GlaxoSmithKline hid the suicidal events in the group of teenag…
#Study329 is a case of scientifuc fraud in psychiatry. GlaxoSmithKline hid the suicidal events in the group of teenagers 12-18 y.o. treated with antidepressant paroxetine. GSK published falsified results in a leading journal and brainwashed psychiatrists
@Foreman1David @benzosarebad @DrFulli @RealJesseLuke @alyne_duthie @jill_d35 @BenefitsOfDX @DrEvgenyLegedin @AntheaRogers @AllenFrancesMD BTW: in the original publicaton, there were 5 suic. events with parox. vs. 0 with plac (acute phase). p < 0.05 with
RT @psychepi: @wendyburn bad title, imposed by BJP, gives no hint that Jon Jureidini & I were debating Goran Isacsson & Charles Rich, argui…
@wendyburn bad title, imposed by BJP, gives no hint that Jon Jureidini & I were debating Goran Isacsson & Charles Rich, arguing against claim. Have you seen Restoring Study 329 https://t.co/aJySq7NYiB which found increased suicidality with paroxeti
I suggest citing Le Noury et al. (2015) Restoring Study 329 https://t.co/aJySq85za9 (open access) (which I co-authored, but I would suggest it even if I hadn’t) about the misrepresentation of suicidality (and effectiveness) in #GSK’s #Study329 of #paroxeti
RT @medsconsult: Prince Harry should watch my presentation https://t.co/xREsZoOGsD https://t.co/OtwSWsXl3t
Prince Harry should watch my presentation https://t.co/xREsZoOGsD
RT @Truthman30: I'm sure Prince Harry is unaware that the sponsors of Wellchild (GSK) are convicted criminal felons? responsible for lying…
/11 This all came to light in 2015 when the first RIAT (Restoring Invisible and Abandoned Trials) was published in BMJ. paper is here: https://t.co/ae5gCWnbi8 These authors pored over 77,000+ pages of internal study documents to re-analyze #study329 per
/2 #Study329 was a GlaxoSmithKline sponsored 8-week randomized controlled trial of paroxetine vs. placebo (with the active comparator, imipramine, the old tricyclic #antidepressant) in depressed adolescents. Original 2001 article by Keller here: https:
@skeptishrink @alyne_duthie For example https://t.co/UhTVDEGD5C
RT @Truthman30: and furthermore these (non informative) leaflets were printed in 2013!!! There has been much more research done in the last…
#mentalhealth “Neither paroxetine nor high dose imipramine showed efficacy for major depression in adolescents, and there was an increase in harms with both drugs“
@jillianbmiles @neveryoumindok @DebbieHayton @guardian Gender questioning kids deserve the same high standards of safe prescribing as any other patient surely? Given the tragic learnings from Study 329 re drug effects on MH why aren't people demanding RCTs
@TheProject_Ed @StopFundingHate @martybhoy07 @Mermaids_Gender Gender questioning kids deserve the same high standards of safe prescribing as any other patient surely? Given the tragic learnings from Study 329 re drug effects on MH why aren't people demandi
@NyssaDogFriend @HJJoyceEcon @StopFundingHate Gender questioning kids deserve the same high standards of safe prescribing as any other patient surely? Given the tragic learnings from Study 329 re drug effects on MH why aren't people demanding RCTs to ensur
@Genderintell @Mermaids_Gender @rcgp @AdrianHarrop @Transgendertrd @stonewalluk @BBCNewsnight @HealthWatchUK The link to study 329 https://t.co/t0uIzBycGX and here https://t.co/RjQuWpyIFI. Because everyone deserves high (not double) standards of evidence.
@garridino @Giulianodalcin1 @angy_cocco @GiuliaGrilloM5S @MinisteroSalute @Corvelva @CorlEva sì, hanno fatto analisi. E bastava fare una controanalisi, invece ci si è fidati delle case farmaceutiche. Come per la Paroxetina (Glaxo) https://t.co/GMRSEviX0P
Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence https://t.co/3hV6kkXiJ1
@tmarshallmph @AliBeckZeck Too bad. Your limited, inflexible reading style keeps you from educating yourself and widening your limited med school education. Read some Healy, Breggin, Gøtzsche, Moncrieff, Whitaker, and actually learn something. https://t.c
RT @Martin_Ploederl: When the Keller et al. (2001) study (Study 329) was debunked by Jureidini et al. (https://t.co/I6L2DVocGp). Do you kno…
RT @psychepi: Karen Dineen Wagner is President of AACAP https://t.co/bOSo2GC7WJ Stan Kutcher is a Canadian Senator https://t.co/btFv5sR0SM…
Karen Dineen Wagner is President of AACAP https://t.co/bOSo2GC7WJ Stan Kutcher is a Canadian Senator https://t.co/btFv5sR0SM previously Head of Psychiatry at Dalhousie
RT @Martin_Ploederl: When the Keller et al. (2001) study (Study 329) was debunked by Jureidini et al. (https://t.co/I6L2DVocGp). Do you kno…
When the Keller et al. (2001) study (Study 329) was debunked by Jureidini et al. (https://t.co/I6L2DVocGp). Do you know if this had any academic or legal consequences for Keller or his co-authors?
RT @VaxChoiceVT: 2015 Re-Analysis of Safety Data on "PAXIL" for #Teen Depression is Very Revealing. Meanwhile, Agencies Step in to do "#Sui…
2015 Re-Analysis of Safety Data on "PAXIL" for #Teen Depression is Very Revealing. Meanwhile, Agencies Step in to do "#Suicide Prevention" ... but the Medicines Continue to Flow.... https://t.co/7tcZxiArdM https://t.co/7tcZxiArdM
Zie @volkskrant (2015): Producent antidepressivum verzwijgt risico op zelfmoord. Studie: ‘Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence’ https://t.co/7yCkVXwZHA https://t.co/Zbt6eMzJjh
Lo studio 329 del 2001 in cui si registrava un'efficacia all'uso di paroxetina e imipramina, nel trattamento della depressione tra adolescenti, fu quindi ribaltato: non vi era nessun dato statisticamente o clinicamente diverso dal placebo. https://t.co/tob
The postdoc fellowship is named in honour of #MickeyNardo #1BoringOldMan who worked with us on #RestoringStudy329 https://t.co/Rwr5QrUGBE
@WeCareAboutMH Journals not even retract papers when they have been shown to be fraudulent. Eg the Keller et al (2001) trial remains in the literature and and is still cited although it has been clearly shown that this work is the result of scientific misc
@wendyburn @Truthman30 Oh, unfortunately it‘s very true. See for instance the re-analysis of trial 329. It‘s clearly fraud. Plain and simple. https://t.co/fciemSBxB8
Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence https://t.co/7aypzpNJQS #nationalwritingday
The #NationalWritingDay hashtag is trending on Twitter. Without further ado... Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence (2015) https://t.co/5K7x7OWQUC
He made a significant contribution when he was part of a team that re-evaluated clinical trial data for "Study 329" which evaluated the clinical efficacy of Paxil (the drug I was on for 15 years). https://t.co/DOf4lW9fGc
Transparency, transparency and more transparency, can never Have more of it! Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence https://t.co/j5e6PTf00Q
eficacia y daños de la paroxetina y la imipramina en el tratamiento de la depresión mayor en la adolescencia https://t.co/DaP1j2GvSr
Ni la paroxetina ni la dosis alta de imipramina mostraron eficacia para la depresión mayor en adolescentes, y hubo un aumento en los daños con ambos fármacos. https://t.co/DaP1j2GvSr
"Neither paroxetine nor high dose imipramine showed efficacy for major depression in adolescents, and there was an increase in harms with both drugs" - can we really not trust the data? How can we trust the data? #hkneuro https://t.co/d9Aey0ycD9
@ProfDFrancis @RogueRad @drjohnm https://t.co/0o7xWQBc6e Takedown of study in adolescents claiming “well tolerated” and effective in original publication.
RT @trished: Can we trust the data? Well...Ioannidis cites independent analysis of Study 329 #RIAT @bmj_latest #EBHC2017 https://t.co/vvH…
Can we trust the data? Well...Ioannidis cites independent analysis of Study 329 #RIAT @bmj_latest #EBHC2017 https://t.co/vvHjI7XWbK
He was once U.K. psychiatrist with highest payments from Pharma. + thousands from each of number of expert witness gigs in US https://t.co/GKbYHe0XPw
RT @Zia_Julia: @CoyneoftheRealm Maybe you are unaware but @DrDavidHealy has an actual livelihood outside of expert witness trials. As for i…
@CoyneoftheRealm Maybe you are unaware but @DrDavidHealy has an actual livelihood outside of expert witness trials. As for instance https://t.co/hrS3xPrIcx
Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence https://t.co/opWURGPIpU
Mickey Nardo, co-author of this paper https://t.co/nMxKtHA1mX that debunked a very flawed but influential anti-depressant study, has died.
RT @pharmagossip: Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence http…
RT @pharmagossip: Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence http…
Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence https://t.co/geU5Nhzb0t
RT @CoyneoftheRealm: Restoring Study 329: efficacy, harms of paroxetine and imipramine in treating major depression in adolescence 2/2 http…
RT @LREwoke: @magyetz Study 329 protocol violation and raw data revealed a drug lacking efficacy and safety. https://t.co/GMwtWEUw0o
RT @LREwoke: @magyetz Study 329 protocol violation and raw data revealed a drug lacking efficacy and safety. https://t.co/GMwtWEUw0o
RT @LREwoke: @magyetz Study 329 protocol violation and raw data revealed a drug lacking efficacy and safety. https://t.co/GMwtWEUw0o
RT @anntocoo: GSK社の抗うつ薬パキシル(パロキセチン)、若者には効果なく危険-利益相反のある研究者により隠ぺい・抑制されていた治験データの再分析から判明 ブリティッシュ・メディカル・ジャーナル https://t.co/zHPNNb4ns8
RT @anntocoo: GSK社の抗うつ薬パキシル(パロキセチン)、若者には効果なく危険-利益相反のある研究者により隠ぺい・抑制されていた治験データの再分析から判明 ブリティッシュ・メディカル・ジャーナル https://t.co/zHPNNb4ns8
RT @anntocoo: GSK社の抗うつ薬パキシル(パロキセチン)、若者には効果なく危険-利益相反のある研究者により隠ぺい・抑制されていた治験データの再分析から判明 ブリティッシュ・メディカル・ジャーナル https://t.co/zHPNNb4ns8
RT @bmj_company: The BMJ: Reanalysis of trial data finds paroxetine ineffective & unsafe for adolescents http://t.co/StZiORbiWM http://t.co…
RT @macordero: Paroxetine & imipramine a good example of relevance in access to primary data from clinical trials. Null effects &⬆ harmful…
Paroxetine & imipramine a good example of relevance in access to primary data from clinical trials. Null effects &⬆ harmful for adolescents https://t.co/y5qSF8WkWQ
Restoring Study 329: efficacy, harms of paroxetine and imipramine in treating major depression in adolescence 2/2 https://t.co/Ye44PQ5O4n
Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence https://t.co/wMvIFxN2O0
@bengoldacre not an overview, but the articles re: #study329 https://t.co/wnsrCOzuCh illustrate why open science is a goodly thing
Wilson now explores "Restoring Study 329" which re-analysed the data from the GlaxoSmithKline trial https://t.co/7ysKqDm0lM
Conflicts of interest in #antidepressant studies:Strike 1 https://t.co/15bDfnvr9o two https://t.co/VibQxGDdXy three https://t.co/PbCFu2rXmd
Do feel free to search https://t.co/oI2vZYAXX7 And yes, accessed ++ as many papers are eg https://t.co/vvHjI7GkNa https://t.co/dFHUiB4xAB
Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence https://t.co/0eWOL26YNF
multiple imputation… Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depr https://t.co/8lFf7jNBa0
@in_psych @DrAPitman https://t.co/Dfs0aAd87b - Read BMJ recent studies of Primary CT data before quoting rigged stats.
Rigged CTtrials not evidence. See Primary CT data & protocols for true #antidepressant #ADRs https://t.co/Dfs0aAd87b https://t.co/bgN5Vgrehe
RT @JoannaLeNoury: So if this makes me a parasite...so be it! https://t.co/zA3XbolW89 https://t.co/oJZmtyP26E, @DrDavidHealy @dataparasite
Psicofarmaci: Gli antidepressivi per bambini e adolescenti a base di Paroxetina sono pericolosi, stimolano... https://t.co/YFhCtZXkGP
@bengoldacre @trished @COMPare_Trials Why is BMJ publishing trials w/o https://t.co/N6IRCqeDQc IDs? Eg https://t.co/cGlJT8EMwE