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High prevalence and incidence of HIV-1 in a counseling and testing center in the city of Itajaí, Brazil

Overview of attention for article published in Brazilian Journal of Infectious Diseases, September 2015
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Title
High prevalence and incidence of HIV-1 in a counseling and testing center in the city of Itajaí, Brazil
Published in
Brazilian Journal of Infectious Diseases, September 2015
DOI 10.1016/j.bjid.2015.08.001
Pubmed ID
Authors

Grinberg, Gorki, Giron, Leila Bertoni, Knoll, Rosalie Kupka, Galinskas, Juliana, Camargo, Michelle, Arif, Muhammad Shoaib, Samer, Sadia, Janini, Luiz Mario Ramos, Sucupira, Maria Cecilia Araripe, Diaz, Ricardo Sobhie

Abstract

Itajaí is a port city in southern Brazil with one of the highest incidence and mortality rates from AIDS in the country. The prevalence and incidence of HIV infection were investigated in 1085 of 3196 new HIV-1 infection cases evaluated in the counseling and testing center (CTC) of Itajaí from January 2002 to August 2008. Recent infections were assessed using the BED™, and pol region sequencing was performed in 76 samples. The prevalence ranged from 3.08% to 6.17% among women and from 10.26% to 17.36% among men. A total of 17% of infections were classified as recent (RI), with annual incidence varying from 1.6% to 4.8 per 100 PY among women and from 2.05% to 8.5 per 100 PY among men. Pol sequences were obtained from 38 randomly RI selected individuals: 71% were infected by subtype C, 24% B, 2% D, and 2% F1. Among 38 subjects with established infection (EI), 76% were subtype C, and 24% B. Transmitted drug resistance (TDR) was detected in 18.4% of RI subjects (7.8% to NRTI, 5.2% to NNRTI, and 5.2% PIs) and 5.2% of subjects with EI had NRTI resistance. The high prevalence and incidence of HIV infection in this region is unprecedented in studies involving cases evaluated in CTCs in Brazil.

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Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 21%
Student > Master 5 18%
Student > Ph. D. Student 4 14%
Student > Doctoral Student 3 11%
Researcher 2 7%
Other 4 14%
Unknown 4 14%
Readers by discipline Count As %
Medicine and Dentistry 9 32%
Nursing and Health Professions 4 14%
Agricultural and Biological Sciences 2 7%
Business, Management and Accounting 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 3 11%
Unknown 8 29%