Optimizing cancer genome sequencing and analysis https://t.co/oqHRhnEYDf
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@iskander @BenjaminGVincen This is true - see our paper here (and a movie/gif in the supplement): https://t.co/KbPHWSl7MP But I don't know any tools that attempt to "smooth" this (other than through clustering of VAFs)
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RT @chrisamiller: @CFlensburg For sure. It'll be expensive and comparatively hard, though. We took a stab at it here with a real tumor and…
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@CFlensburg For sure. It'll be expensive and comparatively hard, though. We took a stab at it here with a real tumor and got some answers: https://t.co/e3dNUA2Fx0 I think at the end of the day, you need cell lines to simulate somatic events down to 1% VAF