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Antimicrobial and cytotoxic effects of phosphoric acid solution compared to other root canal irrigants

Overview of attention for article published in Journal of Applied Oral Science, April 2015
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Title
Antimicrobial and cytotoxic effects of phosphoric acid solution compared to other root canal irrigants
Published in
Journal of Applied Oral Science, April 2015
DOI 10.1590/1678-775720130691
Pubmed ID
Authors

Maíra PRADO, Emmanuel João Nogueira Leal da SILVA, Thais Mageste DUQUE, Alexandre Augusto ZAIA, Caio Cezar Randi FERRAZ, José Flávio Affonso de ALMEIDA, Brenda Paula Figueiredo de Almeida GOMES

Abstract

Phosphoric acid has been suggested as an irrigant due to its effectiveness in removing the smear layer. The purpose of this study was to compare the antimicrobial and cytotoxic effects of a 37% phosphoric acid solution to other irrigants commonly used in endodontics. The substances 37% phosphoric acid, 17% EDTA, 10% citric acid, 2% chlorhexidine (solution and gel), and 5.25% NaOCl were evaluated. The antimicrobial activity was tested against Candida albicans, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Actinomyces meyeri, Parvimonas micra, Porphyromonas gingivalis, and Prevotella nigrescens according to the agar diffusion method. The cytotoxicity of the irrigants was determined by using the MTT assay. Phosphoric acid presented higher antimicrobial activity compared to the other tested irrigants. With regard to the cell viability, this solution showed results similar to those with 5.25% NaOCl and 2% chlorhexidine (gel and solution), whereas 17% EDTA and 10% citric acid showed higher cell viability compared to other irrigants. Phosphoric acid demonstrated higher antimicrobial activity and cytotoxicity similar to that of 5.25% NaOCl and 2% chlorhexidine (gel and solution).

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 73 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 18%
Student > Master 12 16%
Student > Postgraduate 10 14%
Student > Bachelor 8 11%
Student > Ph. D. Student 6 8%
Other 13 18%
Unknown 11 15%
Readers by discipline Count As %
Medicine and Dentistry 37 51%
Biochemistry, Genetics and Molecular Biology 4 5%
Materials Science 3 4%
Agricultural and Biological Sciences 3 4%
Chemistry 2 3%
Other 8 11%
Unknown 16 22%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2015.
All research outputs
#14,625,319
of 16,581,438 outputs
Outputs from Journal of Applied Oral Science
#192
of 235 outputs
Outputs of similar age
#206,441
of 251,641 outputs
Outputs of similar age from Journal of Applied Oral Science
#2
of 2 outputs
Altmetric has tracked 16,581,438 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 235 research outputs from this source. They receive a mean Attention Score of 2.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.