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Incidence and predictors of Lhermitte’s sign among patients receiving mediastinal radiation for lymphoma

Overview of attention for article published in Radiation Oncology, September 2015
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Title
Incidence and predictors of Lhermitte’s sign among patients receiving mediastinal radiation for lymphoma
Published in
Radiation Oncology, September 2015
DOI 10.1186/s13014-015-0504-7
Pubmed ID
Authors

Bassem Youssef, JoAnn Shank, Jay P. Reddy, Chelsea C. Pinnix, George Farha, Mani Akhtari, Pamela K. Allen, Michelle A. Fanale, John A. Garcia, Patricia H. Horace, Sarah Milgrom, Grace Li Smith, Yago Nieto, Isadora Arzu, He Wang, Nathan Fowler, Maria Alma Rodriguez, Bouthaina Dabaja

Abstract

To prospectively examine the risk of developing Lhermitte's sign (LS) in patients with lymphoma treated with modern-era chemotherapy followed by consolidation intensity-modulated radiation therapy. We prospectively interviewed all patients with lymphoma who received irradiation to the mediastinum from July 2011 through April 2014. We extracted patient, disease, and treatment-related variables from the medical records of those patients and dosimetric variables from treatment-planning systems and analyzed these factors to identify potential predictors of LS with Pearson chi-square tests. During the study period 106 patients received mediastinal radiation for lymphoma, and 31 (29 %) developed LS. No correlations were found between LS and any of the variables examined, including total radiation dose, maximum point dose to the spinal cord, volume receiving 105 % of the dose, and volumes receiving 5 or 15 Gy. In this group of patients, treatment with chemotherapy followed by intensity-modulated radiation therapy led to 29 % developing LS; this symptom was independent of radiation dose and seemed to be an idiosyncratic reaction. This relatively high incidence could have resulted from prospective use of a structured interview.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 27%
Researcher 3 20%
Student > Doctoral Student 2 13%
Student > Postgraduate 2 13%
Student > Master 2 13%
Other 1 7%
Unknown 1 7%
Readers by discipline Count As %
Medicine and Dentistry 7 47%
Nursing and Health Professions 2 13%
Agricultural and Biological Sciences 1 7%
Arts and Humanities 1 7%
Social Sciences 1 7%
Other 1 7%
Unknown 2 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2016.
All research outputs
#14,266,012
of 23,305,591 outputs
Outputs from Radiation Oncology
#764
of 2,092 outputs
Outputs of similar age
#138,852
of 276,107 outputs
Outputs of similar age from Radiation Oncology
#23
of 59 outputs
Altmetric has tracked 23,305,591 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,092 research outputs from this source. They receive a mean Attention Score of 2.8. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,107 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.