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Revealing Annexin A2 and ARF-6 enrollment during Trypanosoma cruzi extracellular amastigote-host cell interaction

Overview of attention for article published in Parasites & Vectors, September 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Good Attention Score compared to outputs of the same age and source (69th percentile)

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2 X users
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1 Google+ user

Citations

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8 Dimensions

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24 Mendeley
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Title
Revealing Annexin A2 and ARF-6 enrollment during Trypanosoma cruzi extracellular amastigote-host cell interaction
Published in
Parasites & Vectors, September 2015
DOI 10.1186/s13071-015-1097-6
Pubmed ID
Authors

Thaise Lara Teixeira, Lilian Cruz, Renato Arruda Mortara, Claudio Vieira Da Silva

Abstract

Invasion of host cells by Trypanosoma cruzi extracellular amastigotes is host actin polymerization-dependent. However, the role of proteins related to actin dynamics during invasion by amastigotes remains to be investigated. Here we describe the role of Annexin A2 and ARF-6 during extracellular amastigote-mammalian cell interactions. Our results showed ARF-6 accumulation in the amastigote-containing parasitophorous vacuole containing amastigote forms; demonstrated ARF-6 and Annexin A2 critical impact over parasite cell invasion and revealed the effect of Annexin A2 expression on intracellular parasite multiplication. ARF-6 and Annexin A2 are involved in invasion of mammalian cells by T. cruzi amastigotes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 21%
Professor 5 21%
Student > Ph. D. Student 3 13%
Student > Master 3 13%
Student > Bachelor 2 8%
Other 1 4%
Unknown 5 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 33%
Immunology and Microbiology 3 13%
Agricultural and Biological Sciences 2 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Chemistry 1 4%
Other 1 4%
Unknown 8 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 September 2015.
All research outputs
#13,214,454
of 22,829,683 outputs
Outputs from Parasites & Vectors
#2,309
of 5,463 outputs
Outputs of similar age
#125,823
of 274,379 outputs
Outputs of similar age from Parasites & Vectors
#46
of 152 outputs
Altmetric has tracked 22,829,683 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,463 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,379 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 152 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.