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Soluble amyloid precursor protein: a novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin

Overview of attention for article published in Stem Cell Research & Therapy, August 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)

Mentioned by

blogs
1 blog
facebook
1 Facebook page

Citations

dimensions_citation
79 Dimensions

Readers on

mendeley
87 Mendeley
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Title
Soluble amyloid precursor protein: a novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin
Published in
Stem Cell Research & Therapy, August 2011
DOI 10.1186/scrt77
Pubmed ID
Authors

Michael P Demars, Amelia Bartholomew, Zuzana Strakova, Orly Lazarov

Abstract

Soluble amyloid precursor protein α (sAPPα) is a proteolyte of APP cleavage by α-secretase. The significance of the cleavage and the physiological role of sAPPα are unknown. A crystal structure of a region of the amino terminal of sAPPα reveals a domain that is similar to cysteine-rich growth factors. While a previous study implicates sAPPα in the regulation of neural progenitor cell proliferation in the subventricular zone of adult mice, the ubiquitous expression of APP suggests that its role as a growth factor might be broader.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
Portugal 1 1%
Australia 1 1%
Germany 1 1%
Brazil 1 1%
Poland 1 1%
Unknown 80 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 29%
Researcher 10 11%
Student > Master 9 10%
Student > Bachelor 8 9%
Professor 6 7%
Other 12 14%
Unknown 17 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 31%
Neuroscience 18 21%
Biochemistry, Genetics and Molecular Biology 9 10%
Medicine and Dentistry 7 8%
Psychology 1 1%
Other 3 3%
Unknown 22 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2018.
All research outputs
#3,519,497
of 22,656,971 outputs
Outputs from Stem Cell Research & Therapy
#313
of 2,410 outputs
Outputs of similar age
#19,259
of 124,320 outputs
Outputs of similar age from Stem Cell Research & Therapy
#1
of 4 outputs
Altmetric has tracked 22,656,971 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,410 research outputs from this source. They receive a mean Attention Score of 5.0. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 124,320 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them