Title |
Mass-Up: an all-in-one open software application for MALDI-TOF mass spectrometry knowledge discovery
|
---|---|
Published in |
BMC Bioinformatics, October 2015
|
DOI | 10.1186/s12859-015-0752-4 |
Pubmed ID | |
Authors |
H. López-Fernández, H. M. Santos, J. L. Capelo, F. Fdez-Riverola, D. Glez-Peña, M. Reboiro-Jato |
Abstract |
Mass spectrometry is one of the most important techniques in the field of proteomics. MALDI-TOF mass spectrometry has become popular during the last decade due to its high speed and sensitivity for detecting proteins and peptides. MALDI-TOF-MS can be also used in combination with Machine Learning techniques and statistical methods for knowledge discovery. Although there are many software libraries and tools that can be combined for these kind of analysis, there is still a need for all-in-one solutions with graphical user-friendly interfaces and avoiding the need of programming skills. Mass-Up, an open software multiplatform application for MALDI-TOF-MS knowledge discovery is herein presented. Mass-Up software allows data preprocessing, as well as subsequent analysis including (i) biomarker discovery, (ii) clustering, (iii) biclustering, (iv) three-dimensional PCA visualization and (v) classification of large sets of spectra data. Mass-Up brings knowledge discovery within reach of MALDI-TOF-MS researchers. Mass-Up is distributed under license GPLv3 and it is open and free to all users at http://sing.ei.uvigo.es/mass-up . |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 3 | 43% |
Unknown | 4 | 57% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 4 | 57% |
Members of the public | 3 | 43% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 2 | 1% |
Brazil | 2 | 1% |
United Kingdom | 1 | <1% |
Croatia | 1 | <1% |
Madagascar | 1 | <1% |
Unknown | 141 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 34 | 23% |
Student > Ph. D. Student | 26 | 18% |
Student > Master | 17 | 11% |
Student > Bachelor | 11 | 7% |
Student > Doctoral Student | 9 | 6% |
Other | 26 | 18% |
Unknown | 25 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 22 | 15% |
Biochemistry, Genetics and Molecular Biology | 19 | 13% |
Computer Science | 17 | 11% |
Chemistry | 16 | 11% |
Medicine and Dentistry | 13 | 9% |
Other | 26 | 18% |
Unknown | 35 | 24% |