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A study of pulmonary function in end-stage renal disease patients on hemodialysis: a cross-sectional study

Overview of attention for article published in Sao Paulo Medical Journal, January 2017
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Title
A study of pulmonary function in end-stage renal disease patients on hemodialysis: a cross-sectional study
Published in
Sao Paulo Medical Journal, January 2017
DOI 10.1590/1516-3180.2017.0179150817
Pubmed ID
Authors

Ashima Sharma, Ashok Sharma, Sushila Gahlot, Pawan Kumar Prasher

Abstract

The aim here was to study acute effects of hemodialysis among end-stage renal disease (ESRD) patients. Prospective study in tertiary-level care center. Fifty ESRD patients undergoing hemodialysis were studied. Spirometric pulmonary function tests were performed before and after four-hour hemodialysis sessions. The patients' average age was 45.8 ± 10.0 years; 64% were males and 64% had normal body mass index. Anemia (94%) and hypoalbuminemia (72%) were common. Diabetes mellitus (68%), hypertension (34%) and coronary artery disease (18%) were major comorbidities. Forty-five patients (90%) had been on hemodialysis for six months to three years. The patients' pre-dialysis mean forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1) were below normal: 45.8 ± 24.9% and 43.5 ± 25.9% of predicted, respectively. After hemodialysis, these increased significantly, to 51.1 ± 23.4% and 49.3 ± 25.5% of predicted, respectively (P < 0.01). The increase in mean FEV1/FVC, from 97.8 ± 20.8% to 99.3 ± 20.1% of predicted, was not significant (P > 0.05). The pre-dialysis mean forced expiratory flow 25-75% was 50.1 ± 31% and increased significantly, to 56.3 ± 31.6% of predicted (P < 0.05). The mean peak expiratory flow was below normal (43.8 ± 30.7%) and increased significantly, to 49.1 ± 29.9% of predicted (P < 0.05). Males and females showed similar directions of change after hemodialysis. Pulmonary function abnormalities are common among ESRD patients. Comparison of pre and post-hemodialysis parameters showed significant improvements, but normal predicted values were still not achieved.

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Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 19%
Student > Postgraduate 4 15%
Student > Bachelor 2 8%
Student > Ph. D. Student 2 8%
Student > Doctoral Student 1 4%
Other 5 19%
Unknown 7 27%
Readers by discipline Count As %
Medicine and Dentistry 10 38%
Arts and Humanities 2 8%
Environmental Science 2 8%
Psychology 1 4%
Nursing and Health Professions 1 4%
Other 2 8%
Unknown 8 31%