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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Functional implications of Rab27 GTPases in Cancer
|
|---|---|
| Published in |
Cell Communication and Signaling, August 2018
|
| DOI | 10.1186/s12964-018-0255-9 |
| Pubmed ID | |
| Authors |
Zhihong Li, Rui Fang, Jia Fang, Shasha He, Tang Liu |
| Abstract |
The Rab27 family of small GTPases promotes the progression of breast cancer, melanoma, and other human cancers. In this review, we discuss the role of Rab27 GTPases in cancer progression and the potential applications of these targets in cancer treatment. Elevated expression of Rab27 GTPases is associated with poor prognosis and cancer metastasis. Moreover, these GTPases govern a variety of oncogenic functions, including cell proliferation, cell motility, and chemosensitivity. In addition, small GTPases promote tumor growth and metastasis by enhancing exosome secretion, which alters intracellular microRNA levels, signaling molecule expression, and the tumor microenvironment. Rab27 GTPases may have applications as prognostic markers and therapeutic targets in cancer treatment. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 73 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 11 | 15% |
| Student > Ph. D. Student | 10 | 14% |
| Student > Master | 9 | 12% |
| Researcher | 5 | 7% |
| Student > Doctoral Student | 4 | 5% |
| Other | 6 | 8% |
| Unknown | 28 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 18 | 25% |
| Medicine and Dentistry | 7 | 10% |
| Agricultural and Biological Sciences | 6 | 8% |
| Immunology and Microbiology | 4 | 5% |
| Chemistry | 3 | 4% |
| Other | 6 | 8% |
| Unknown | 29 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2018.
All research outputs
#15,542,971
of 23,099,576 outputs
Outputs from Cell Communication and Signaling
#518
of 1,021 outputs
Outputs of similar age
#209,860
of 330,726 outputs
Outputs of similar age from Cell Communication and Signaling
#11
of 29 outputs
Altmetric has tracked 23,099,576 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,021 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,726 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.