Criteria for failure can include: · high toxicity in humans. · Drug has little of an effect. · Drug is removed from circulation too fast and more. More information: https://t.co/s7PGyTTeaD.
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@dw2 @jpsenescence Speed and cost are issues, and I expect they'll be improved, but it seems they don't really *cause* failure. We'd be more patient and pay extra--if these trials succeeded 80% of the time, I suspect...but alas...are people removing these
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Comparing 2012 investigation into ivermectin to inhibit replication of flavivirus as "well-tolerated" and therefore not needing expensive trials with the amount of work going in here: https://t.co/OZTsz8mbeW with 2018 causes of failure in trials: https://t
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✏️ Top 2: “Factors associated with clinical trials that fail and opportunities for improving the likelihood of success: A review" 👇https://t.co/cidn1tlr5s