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The stats are in: an update on statin use in COPD

Overview of attention for article published in International Journal of Chronic Obstructive Pulmonary Disease, October 2015
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1 tweeter

Citations

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14 Dimensions

Readers on

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27 Mendeley
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Title
The stats are in: an update on statin use in COPD
Published in
International Journal of Chronic Obstructive Pulmonary Disease, October 2015
DOI 10.2147/copd.s78875
Pubmed ID
Authors

Debra Reid, Alexa Carlson, Ethan Smith

Abstract

COPD is a chronic inflammatory disease of the lungs associated with an abnormal inflammatory response to noxious particles, the most prevalent of which is cigarette smoke. Studies have demonstrated that cigarette smoking is associated with activation of the bone marrow, and chronic smoking can lead to the inflammatory changes seen in COPD. Due to the inflammatory nature of the disease, medications affecting the inflammatory pathway may have clinical benefit and are being evaluated. One such class of medications, HMG-CoA reductase inhibitors, have been evaluated in the COPD population. Early studies have suggested that HMG-CoA reductase inhibitors have a variety of benefits in COPD including improvements in inflammatory markers, exacerbation rates, and mortality rates. However, the majority of this data comes from retrospective cohort studies, suggesting the need for randomized controlled trials. Recently, two randomized controlled trials, STATCOPE and RODEO, evaluated the benefit of HMG-CoA reductase inhibitors in the COPD population and found no benefit in exacerbation rates and vascular or pulmonary function, respectively. These results are reflected in practice guidelines, which do not support the use of HMG-CoA reductase inhibitors for the purpose of reducing COPD exacerbations.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
Netherlands 1 4%
Unknown 25 93%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 22%
Researcher 5 19%
Student > Doctoral Student 3 11%
Student > Ph. D. Student 3 11%
Student > Bachelor 2 7%
Other 5 19%
Unknown 3 11%
Readers by discipline Count As %
Medicine and Dentistry 10 37%
Pharmacology, Toxicology and Pharmaceutical Science 3 11%
Nursing and Health Professions 2 7%
Biochemistry, Genetics and Molecular Biology 1 4%
Computer Science 1 4%
Other 5 19%
Unknown 5 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 October 2015.
All research outputs
#18,429,163
of 22,830,751 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#1,899
of 2,353 outputs
Outputs of similar age
#197,662
of 274,921 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#75
of 87 outputs
Altmetric has tracked 22,830,751 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,353 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,921 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.